Search

David C Routenberg

from Gaithersburg, MD
Age ~43

David Routenberg Phones & Addresses

  • 12405 Galesville Dr, Gaithersburg, MD 20878
  • San Diego, CA
  • 539 Prospect St, New Haven, CT 06511 (203) 624-5935
  • 539 Prospect St #3, New Haven, CT 06511 (203) 624-5935
  • 382 Whitney Ave, New Haven, CT 06511
  • 10724 Hunters Pl, Vienna, VA 22181 (703) 758-8842
  • Herndon, VA
  • Charlottesville, VA

Publications

Us Patents

Peptide Constructs And Assay Systems

View page
US Patent:
20120258871, Oct 11, 2012
Filed:
Apr 9, 2012
Appl. No.:
13/442637
Inventors:
Igor A. Kozlov - San Diego CA, US
Mark S. Chee - Encinitas CA, US
Petr Capek - San Diego CA, US
David A. Routenberg - San Diego CA, US
Assignee:
PROGNOSYS BIOSCIENCES, INC. - La Jolla CA
International Classification:
C40B 20/04
C40B 40/06
US Classification:
506 4, 506 16
Abstract:
The present invention provides methods for constructing peptide construct sets and methods of use of these peptide construct sets in assay systems for peptide analysis, and in particular for use in high throughput peptide analysis. The methods allow for analysis of large sets of peptide constructs in a cost-effective manner, employing molecular biological techniques that are both robust and easily parallelized. Thus, the methods allow for the construction of peptide construct sets encompassing, e.g., the human proteome.

Methods For Manufacturing Molecular Arrays

View page
US Patent:
20130096033, Apr 18, 2013
Filed:
Dec 3, 2012
Appl. No.:
13/692250
Inventors:
David A. Routenberg - San Diego CA, US
Assignee:
PROGNOSYS BIOSCIENCES, INC. - La Jolla CA
International Classification:
C40B 50/06
US Classification:
506 26
Abstract:
The methods of the present invention provide methods for manufacturing a master substrate and methods for manufacturing replica arrays from the master substrate. The methods may be used, for example, directly to manufacture or “print” peptide arrays from a DNA array; however, the methods are applicable to a wide range of manufacturing applications for use any time multiple copies of an array needs to be printed.

Methods For Manufacturing Molecular Arrays

View page
US Patent:
20130109595, May 2, 2013
Filed:
Oct 28, 2011
Appl. No.:
13/283906
Inventors:
David A. Routenberg - San Diego CA, US
Assignee:
PROGNOSYS BIOSCIENCES, INC. - La Jolla CA
International Classification:
C40B 40/10
C40B 50/06
US Classification:
506 18, 506 26
Abstract:
The methods of the present invention provide methods for manufacturing a master substrate and methods for manufacturing replica arrays from the master substrate. The methods may be used, for example, directly to manufacture or “print” peptide arrays from a DNA array; however, the methods are applicable to a wide range of manufacturing applications for use any time multiple copies of an array needs to be printed.

Peptide Constructs And Assay Systems

View page
US Patent:
20140051589, Feb 20, 2014
Filed:
Oct 31, 2013
Appl. No.:
14/068921
Inventors:
Mark S. CHEE - Encinitas CA, US
Petr CAPEK - San Diego CA, US
David A. ROUTENBERG - San Diego CA, US
International Classification:
G01N 33/68
US Classification:
506 4, 506 16
Abstract:
The present invention provides methods for constructing peptide construct sets and methods of use of these peptide construct sets in assay systems for peptide analysis, and in particular for use in high throughput peptide analysis. The methods allow for analysis of large sets of peptide constructs in a cost-effective manner, employing molecular biological techniques that are both robust and easily parallelized. Thus, the methods allow for the construction of peptide construct sets encompassing, e.g., the human proteome.

Systems And Methods For Cmos-Compatible Silicon Nano-Wire Sensors With Biochemical And Cellular Interfaces

View page
US Patent:
20100297608, Nov 25, 2010
Filed:
Dec 6, 2007
Appl. No.:
12/517230
Inventors:
Eric D. Stern - New Haven CT, US
Tarek M. Fahmy - New Haven CT, US
Mark A. Reed - Monroe CT, US
Andrew Hamilton - Guilford CT, US
David A. Lavan - Hamden CT, US
James F. Klemic - New Haven CT, US
David A. Routenberg - New Haven CT, US
International Classification:
C12Q 1/70
H01L 29/772
H01L 21/302
C12Q 1/02
G01N 33/53
C12Q 1/68
US Classification:
435 5, 257253, 438689, 435 29, 435 71, 435 6, 257E29242, 257E21214
Abstract:
The systems and methods described herein include a sensor for suitable for sensing chemical and biological substances. The sensor comprises a semiconductor layer formed in or on a substrate and a channel having nano-scale dimensions formed in the semiconductor layer, where the structure creates an electrically conducting pathway between a first contact and a second contact on the semiconductor layer. In certain preferred embodiments, the nano-scale channel has a trapezoidal cross-section with an effective width and exposed lateral faces, where the effective width is selected to have same order of magnitude as a Debye length (L) of the semiconductor material of which the semiconductor layer is formed.

Assay Methods

View page
US Patent:
20220357318, Nov 10, 2022
Filed:
Jul 21, 2022
Appl. No.:
17/813965
Inventors:
- Rockville MD, US
Eli N. GLEZER - Del Mar CA, US
John KENTEN - Boyds MD, US
George SIGAL - Rockville MD, US
Martin STENGELIN - Gaithersburg MD, US
David ROUTENBERG - Gaithersburg MD, US
International Classification:
G01N 33/543
C12Q 1/6832
C12Q 1/6837
C12Q 1/6844
Abstract:
The present invention is directed to methods for improving assay specificity and performance in binding assays.

Methods And Systems For Determining Spatial Patterns Of Biological Targets In A Sample

View page
US Patent:
20220325325, Oct 13, 2022
Filed:
Jun 2, 2022
Appl. No.:
17/830923
Inventors:
- San Diego CA, US
David A. ROUTENBERG - San Diego CA, US
Assignee:
Prognosys Biosciences, Inc. - San Diego CA
International Classification:
C12Q 1/6809
Abstract:
The present disclosure provides methods and assay systems for use in spatially encoded biological assays, including assays to determine a spatial pattern of abundance, expression, and/or activity of one or more biological targets across multiple sites in a sample. In particular, the biological targets comprise proteins, and the methods and assay systems do not depend on imaging techniques for the spatial information of the targets. The present disclosure provides methods and assay systems capable of high levels of multiplexing where reagents are provided to a biological sample in order to address tag the sites to which reagents are delivered; instrumentation capable of controlled delivery of reagents; and a decoding scheme providing a readout that is digital in nature.

Peptide Constructs And Assay Systems

View page
US Patent:
20220260581, Aug 18, 2022
Filed:
Apr 22, 2022
Appl. No.:
17/727618
Inventors:
- San Diego CA, US
Mark S. CHEE - San Diego CA, US
Petr CAPEK - San Diego CA, US
David A. ROUTENBERG - San Diego CA, US
Assignee:
Prognosys Biosciences, Inc. - San Diego CA
International Classification:
G01N 33/68
C12N 15/10
Abstract:
The present invention provides methods for constructing peptide construct sets and methods of use of these peptide construct sets in assay systems for peptide analysis, and in particular for use in high throughput peptide analysis. The methods allow for analysis of large sets of peptide constructs in a cost-effective manner, employing molecular biological techniques that are both robust and easily parallelized. Thus, the methods allow for the construction of peptide construct sets encompassing, e.g., the human proteome.
David C Routenberg from Gaithersburg, MD, age ~43 Get Report