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Hongyao W Zhu

from Waterford, CT
Age ~61

Hongyao Zhu Phones & Addresses

  • 15 Arrowhead Trl, Waterford, CT 06385 (512) 426-1949
  • 95 Rockdale Rd, West Haven, CT 06516
  • Cedar Park, TX
  • 7205 Hart Ln, Austin, TX 78731 (512) 794-9360
  • Willimantic, CT
  • Groton, CT
  • Ledyard, CT
  • New London, CT
  • 15 Arrowhead Trl, Waterford, CT 06385 (512) 431-1390

Work

Position: Professional/Technical

Education

Degree: Associate degree or higher

Publications

Us Patents

Compounds Modulating C-Fms And/Or C-Kit Activity And Uses Therefor

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US Patent:
7893075, Feb 22, 2011
Filed:
Nov 21, 2007
Appl. No.:
11/986667
Inventors:
Jiazhong Zhang - Foster City CA, US
Prabha N. Ibrahim - Mountain View CA, US
Dean R. Artis - Kensington CA, US
Ryan Bremer - Oakland CA, US
Guoxian Wu - Palo Alto CA, US
Hongyao Zhu - Cedar Park TX, US
Marika Nespi - Berkeley CA, US
Chao Zhang - Moraga CA, US
Assignee:
Plexxikon, Inc. - Berkeley CA
International Classification:
A61K 31/506
A61K 31/454
A61P 35/00
C07D 471/04
C07D 239/02
US Classification:
514275, 514300, 546113, 544297
Abstract:
Compounds active on the receptor protein tyrosine kinases c-kit and/or c-fms are provided herewith. Also provided herewith are compositions useful for treatment of c-kit mediated diseases or conditions and/or c-fms-mediated diseases or conditions, and methods for the use thereof.

Compounds Modulating C-Fms And/Or C-Kit Activity

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US Patent:
8461169, Jun 11, 2013
Filed:
Dec 1, 2010
Appl. No.:
12/958379
Inventors:
Jiazhong Zhang - Burlingame CA, US
Prabha N. Ibrahim - Mountain View CA, US
Dean R. Artis - Kensington CA, US
Ryan Bremer - Emeryville CA, US
Guoxian Wu - Palo Alto CA, US
Hongyao Zhu - Waterford CT, US
Marika Nespi - Berkeley CA, US
Chao Zhang - Moraga CA, US
Assignee:
Plexxikon Inc. - Berkeley CA
International Classification:
A61K 31/505
A61K 31/44
US Classification:
514275, 514300
Abstract:
Compounds active on the receptor protein tyrosine kinases c-kit and/or c-fms are provided herewith. Also provided herewith are compositions useful for treatment of c-kit mediated diseases or conditions and/or c-fms-mediated diseases or conditions, and methods for the use thereof.

Compounds And Uses Thereof

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US Patent:
20100286178, Nov 11, 2010
Filed:
Mar 10, 2010
Appl. No.:
12/721496
Inventors:
Prabha N. Ibrahim - Mountain View CA, US
Wayne Spevak - Berkeley CA, US
Hanna Cho - Oakland CA, US
Hongyao Zhu - Waterford CT, US
International Classification:
A61K 31/513
C07D 401/14
C07D 471/04
A61K 31/437
A61P 35/00
US Classification:
514274, 544316, 546113, 514300
Abstract:
Propane--sulfonic acid {2,4-difluoro-3-[5-(2-methoxy-pyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-phenyl}-amide, propane-1-sulfonic acid [3-(5-cyano-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluoro-phenyl]-amide, propane-1-sulfonic acid [3-(5-cyano-1H-pyrrolo [2,3-b]pyridine-3-carbonyl)-2-fluoro-phenyl]-amide, N-[3-(5-cyano-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluoro-phenyl]-2,5-difluoro-benzenesulfonamide, N-[3-(5-cyano-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluoro-phenyl]-3-fluoro-benzenesulfonamide, pyrrolidine-1-sulfonic acid [3-(5-cyano-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluoro-phenyl]-amide, N,N-dimethylamino-sulfonic acid [3-(5-cyano-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluoro-phenyl]-amide, and salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof and uses thereof are described. In certain aspects and embodiments, the described compounds or salts thereof, formulations thereof, conjugates thereof, derivatives thereof, and forms thereof are active on at least one Raf protein kinase. Also described are methods of use thereof to treat diseases and conditions, including diseases and conditions associated with activity of Raf protein kinases, including melanoma, glioma, colorectal cancer, thyroid cancer, lung cancer, ovarian cancer, prostate cancer, and biliary tract cancer.

Compounds Modulating C-Fms And/Or C-Kit Activity And Uses Therefor

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US Patent:
20190263800, Aug 29, 2019
Filed:
Oct 1, 2018
Appl. No.:
16/148244
Inventors:
- Berkeley CA, US
Prabha N. Ibrahim - Mountain View CA, US
Dean R. Artis - Kensington CA, US
Ryan Bremer - Emeryville CA, US
Guoxian Wu - Palo Alto CA, US
Hongyao Zhu - Cedar Park TX, US
Marika Nespi - Berkeley CA, US
Chao Zhang - Moraga CA, US
International Classification:
C07D 471/04
A61K 45/06
A61K 31/5377
A61K 31/444
A61K 31/497
A61K 31/506
Abstract:
Compounds active on the receptor protein tyrosine kinases c-kit an or c-fms are provided herewith. Also provided herewith are compositions useful for treatment of c-kit mediated diseases or conditions and/or c-fms-mediated diseases or conditions, and methods for the use thereof.

Compounds Modulating C-Fms And/Or C-Kit Activity And Uses Therefor

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US Patent:
20170247370, Aug 31, 2017
Filed:
Oct 7, 2016
Appl. No.:
15/288558
Inventors:
- Berkeley CA, US
Prabha N. Ibrahim - Mountain View CA, US
Dean R. Artis - Kensington CA, US
Ryan Bremer - Emeryville CA, US
Guoxian Wu - Palo Alto CA, US
Hongyao Zhu - Cedar Park TX, US
Marika Nespi - Berkeley CA, US
Chao Zhang - Moraga CA, US
International Classification:
C07D 471/04
Abstract:
Compounds active on the receptor protein tyrosine kinases c-kit and/or c-fms are provided herewith. Also provided herewith are compositions useful for treatment of c-kit mediated diseases or conditions and/or c-fms-mediated diseases or conditions, and methods for the use thereof.
Hongyao W Zhu from Waterford, CT, age ~61 Get Report