Inventors:
Stephen C. Bergmeier - Athens OH, US
Nigel D. Priestley - Alberton MT, US
Assignee:
OHIO UNIVERSITY - Athens OH
International Classification:
C07D 405/14
C07D 405/06
C07D 413/14
US Classification:
544121, 548255, 544366, 546210, 544357
Abstract:
Methyl nonactate is converted into a variety of different triazoloamide antibacterial agents by a reaction scheme involving (1) inversion of the secondary alcohol of the methyl nonactate to produce the corresponding azidoester, (2) converting the azido ester to the corresponding azidoamide, and (3) converting the azido group of the azidoamide to a triazole to produce the corresponding triazoloamide.