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Aren Ewing Phones & Addresses

  • Carlsbad, CA
  • Brisbane, CA
  • 49 Van Buren St, San Francisco, CA 94131
  • Walnut Creek, CA
  • San Mateo, CA
  • Honolulu, HI
  • Davis, CA
  • Burlingame, CA

Work

Company: Hungry riders Jun 2012 Position: Creator / producer / host

Education

Degree: MS School / High School: University of Hawaii at Manoa 2003 to 2008 Specialities: Molecular Biosciences and Bioengineering - Bioinformatics

Skills

Molecular Biology • Bioinformatics • Informatics • Genomics • Biochemistry • Genetics • Computational Biology • Sequencing • Sequence Analysis • Cell Culture • Proteomics • Life Sciences • DNA • Protein Chemistry • PCR • Biotechnology • Immunology • Systems Biology • Protein Expression • Protein Purification • Functional Genomics • Comparative Genomics • Virology

Interests

Biotech, Bioinformatics, start up compan...

Industries

Biotechnology

Resumes

Resumes

Aren Ewing Photo 1

Bioinformatics Scientist - Genome Curation At Solazyme, Inc.

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Position:
Bioinformatics Scientist - Genome Curation at Solazyme, Inc., Creator / Producer / Host at Hungry Riders
Location:
San Francisco Bay Area
Industry:
Biotechnology
Work:
Hungry Riders since Jun 2012
Creator / Producer / Host

Vista Informatics - San Francisco Bay Area since Apr 2012
Bioinformatics Consultant

Joint Genome Institute Dec 2009 - Apr 2012
Bioinformatics Analyst

Hoffmann-La Roche Aug 2008 - Dec 2009
Research Scientist (Contractor)

University of Hawaii at Manoa 2003 - 2008
Graduate research Assistant
Education:
University of Hawaii at Manoa 2003 - 2008
MS, Molecular Biosciences and Bioengineering - Bioinformatics
University of California, Davis 1998 - 2002
BS, Biochemistry and Molecular Biology
Skills:
Molecular Biology
Bioinformatics
Informatics
Genomics
Biochemistry
Genetics
Computational Biology
Sequencing
Sequence Analysis
Cell Culture
Proteomics
Life Sciences
DNA
Protein Chemistry
PCR
Biotechnology
Immunology
Systems Biology
Protein Expression
Protein Purification
Functional Genomics
Comparative Genomics
Virology
Interests:
Biotech, Bioinformatics, start up companies, investment, entrepreneurship, product development, scuba diving, motorcycles, rock climbing

Publications

Us Patents

Compositions And Methods For Oncology Precision Assays

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US Patent:
20230112730, Apr 13, 2023
Filed:
Aug 15, 2022
Appl. No.:
17/887727
Inventors:
- Carlsbad CA, US
Aren Ewing - Carlsbad CA, US
Na Li - Foster City CA, US
Zunping Luo - Redwood City CA, US
Amir Marcovitz - Menlo Park CA, US
Assignee:
Life Technologies Corporation - Carlsbad CA
International Classification:
C12Q 1/6886
Abstract:
Provided are methods and compositions for preparing a library of target nucleic acid sequences that are useful for assessing gene mutations for oncology biomarker profiling of samples. In particular, a target-specific primer panel is provided that allows for selective amplification of oncology biomarker target sequences in a sample. In one aspect, the invention relates to target-specific primers useful for selective amplification of one or more target sequences associated with oncology biomarkers from two or more sample types. In some aspects, amplified target sequences obtained using the disclosed methods, and compositions can be used in various processes including nucleic acid sequencing and used to detect the presence of genetic variants of one or more targeted sequences associated with oncology.

Compositions And Methods For Oncology Precision Assays

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US Patent:
20210062271, Mar 4, 2021
Filed:
Aug 28, 2020
Appl. No.:
16/948046
Inventors:
- Carlsbad CA, US
Aren EWING - Carlsbad CA, US
Na LI - Foster City CA, US
Zunping LUO - Redwood City CA, US
Amir MARCOVITZ - Menlo Park CA, US
International Classification:
C12Q 1/6886
Abstract:
Provided are methods and compositions for preparing a library of target nucleic acid sequences that are useful for assessing gene mutations for oncology biomarker profiling of samples. In particular, a target-specific primer panel is provided that allows for selective amplification of oncology biomarker target sequences in a sample. In one aspect, the invention relates to target-specific primers useful for selective amplification of one or more target sequences associated with oncology biomarkers from two or more sample types. In some aspects, amplified target sequences obtained using the disclosed methods, and compositions can be used in various processes including nucleic acid sequencing and used to detect the presence of genetic variants of one or more targeted sequences associated with oncology.

Novel Acyltransferases, Variant Thioesterases, And Uses Thereof

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US Patent:
20200392470, Dec 17, 2020
Filed:
Aug 20, 2020
Appl. No.:
16/998268
Inventors:
- South San Francisco CA, US
Jason Casolari - Palo Alto CA, US
Xinhua Zhao - Dublin CA, US
Aren Ewing - South San Francisco CA, US
Aravind Somanchi - Redwood City CA, US
Scott Franklin - La Jolla CA, US
David Davis - South San Francisco CA, US
International Classification:
C12N 9/10
C12N 15/82
C12P 7/64
Abstract:
Disclosed are microalgal cells having an ablated or downregulated fatty acyl-ACP thioesterase (FATA) gene, wherein the cell is modified to express a heterologous lysophosphatidic acid acyltransferase (LPAAT) comprising an amino acid sequence that has at least 80% identity to an acyltransferase encoded by SEQ ID NO: 90, 89, 92, 93 or 95 and wherein the modified microalgal cell produces an oil with an elevated ratio of saturated-unsaturated-saturated triglycerides over trisaturated triglycerides as compared to a corresponding unmodified cell. Also disclosed are microalgal oils comprising at least 60% stearate-oleate-stearate (SOS) triglycerides, less than 5% trisaturates and wherein the fatty acid profile of the oil comprises at least 50% C18:0. Related methods of producing an oil are also disclosed.

Novel Ketoacyl Acp Synthase Genes And Uses Thereof

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US Patent:
20190345463, Nov 14, 2019
Filed:
Apr 18, 2019
Appl. No.:
16/388817
Inventors:
- South San Francisco CA, US
George Rudenko - Mountain View CA, US
Aravind Somanchi - Redwood City CA, US
Jason Casolari - Palo Alto CA, US
Scott Franklin - Woodside CA, US
Aren Ewing - Brisbane CA, US
International Classification:
C12N 9/10
C12P 7/64
C12P 33/00
C12N 15/82
Abstract:
The present invention relates to beta-ketoacyl ACP synthase genes of the KASI/KASIV type and proteins encoded by these genes. The genes can be included in nucleic acid constructs, vectors or host cells. Expression of the gene products can alter the fatty acid profile of host cells. The KAS genes can be combined with a FATA or FATB thioesterase gene to create a cell that produces an increased amount of C8-C16 fatty acids. Suitable host cells include plastidic cells of plants or microalgae. Oleaginous microalga host cells with the new genes are disclosed.

Novel Ketoacyl Acp Synthase Genes And Uses Thereof

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US Patent:
20180230442, Aug 16, 2018
Filed:
Apr 10, 2018
Appl. No.:
15/950048
Inventors:
- South San Francisco CA, US
George N. Rudenko - Mountain View CA, US
Aravind Somanchi - Redwood City CA, US
Jason Casolari - Palo Alto CA, US
Scott Franklin - Woodside CA, US
Aren Ewing - South San Francisco CA, US
International Classification:
C12N 9/10
C12P 33/00
C12P 7/64
C12N 15/82
Abstract:
The present invention relates to beta-ketoacyl ACP synthase genes of the KASI/KASIV type and proteins encoded by these genes. The genes can be included in nucleic acid constructs, vectors or host cells. Expression of the gene products can alter the fatty acid profile of host cells. The KAS genes can be combined with a FATA or FATB thioesterase gene to create a cell that produces an increased amount of C8-C16 fatty acids. Suitable host cells include plastidic cells of plants or microalgae. Oleaginous microalga host cells with the new genes are disclosed.

Novel Acyltransferases, Variant Thioesterases, And Uses Thereof

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US Patent:
20180142218, May 24, 2018
Filed:
Oct 4, 2017
Appl. No.:
15/725222
Inventors:
- South San Francisco CA, US
Jason Casolari - Palo Alto CA, US
Xinhua Zhao - Dublin CA, US
Aren Ewing - South San Francisco CA, US
Aravind Somanchi - Redwood City CA, US
Scott Franklin - La Jolla CA, US
David Davis - South San Francisco CA, US
International Classification:
C12N 9/10
C12P 7/64
C12N 15/82
Abstract:
Recombinant nucleic acids and vector constructs encoding acyltransferases and variant thioesterases, and the acyltransferases and variant thioesterases encoded by the nucleic acids are provided. The acyltransferases and variant thioesterases are useful in fatty acid synthesis and triacylglycerol production. Host cells that express the recombinant nucleic acids as well as methods of cultivating the host cells, methods of producing oils from the host cells are provided. The recombinant host cells and the oils produced therefrom have altered fatty acid profiles and/or triacylglycerols with altered regiospecificity.

Novel Ketoacyl Acp Synthase Genes And Uses Thereof

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US Patent:
20160010066, Jan 14, 2016
Filed:
Jul 10, 2015
Appl. No.:
14/796406
Inventors:
- South San Francisco CA, US
George Rudenko - Mountain View CA, US
Aravind Somanchi - Redwood City CA, US
Jason Casolari - Palo Alto CA, US
Scott Franklin - Woodside CA, US
Aren Ewing - Brisbane CA, US
International Classification:
C12N 9/10
C12P 7/64
Abstract:
The present invention relates to beta-ketoacyl ACP synthase genes of the KASI/KASIV type and proteins encoded by these genes. The genes can be included in nucleic acid constructs, vectors or host cells. Expression of the gene products can alter the fatty acid profile of host cells. The KAS genes can be combined with a FATA or FATB thioesterase gene to create a cell that produces an increased amount of C8-C16 fatty acids. Suitable host cells include plastidic cells of plants or microalgae. Oleaginous microalga host cells with the new genes are disclosed.

Genetically Engineered Microbial Strains Including Chlorella Protothecoides Lipid Pathway Genes

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US Patent:
20140178950, Jun 26, 2014
Filed:
Dec 6, 2013
Appl. No.:
14/099704
Inventors:
- South San Francisco CA, US
Shane Brubaker - El Cerrito CA, US
George N. Rudenko - Mountain View CA, US
Riyaz Bhat - South San Francisco CA, US
Matthew Shoa-Azar - San Mateo CA, US
Aravind Somanchi - Redwood City CA, US
Aren Ewing - South San Francisco CA, US
Assignee:
Solazyme, Inc. - South San Francisco CA
International Classification:
C12P 7/64
US Classification:
435134, 4353201, 4352572
Abstract:
Genetically engineered microbial, e.g., , cells producing microbial oils are useful as a food additive and a source of renewable fuels and industrial chemicals. Lipid biosynthesis genes for are disclosed that are useful for increasing lipid production and altering fatty acid and triacylglycerol profiles in recombinant microrganisms including cells of the genus or
Aren M Ewing from Carlsbad, CA, age ~44 Get Report