Branson W Ritchie

6491921, Dec 10, 2002

May 4, 1998

09/072634

Steven Poet - Winterville GA
Branson W. Ritchie - Athens GA
Victoria Burnley - Athens GA
Denise Pesti - Athens GA

University of Georgia Research Foundation Inc. - Athens GA

A61K 3912

4241861, 4241841, 4242041, 424278, 424 1, 435 71, 435 693, 435 701, 4352351, 435243, 4353201, 435325, 514 44, 530350, 536 2372

The invention provides a nucleic acid vaccine which is protective against avian polyomavirus infection in a bird which is classified as being a member of the order comprising a nucleic acid vaccine vector comprising a suitable eukaryotic cis-acting transcription/translation regulatory sequence functionally linked to a nucleic acid encoding an immunogenic avian polyomarvirus polypeptide. Methods for preventing avian polyomarvirus infection in a bird classified as being a member of the order, are also provided.

6518252, Feb 11, 2003

Sep 18, 2001

09/954965

Richard E. Wooley - Athens GA
Branson W. Ritchie - Athens GA
Victoria V. Burnley - Bogart GA

University of Georgia Research Foundation, Inc. - Athens GA

A61K 3170

514 29, 514 6, 514 31, 514 34, 514 37, 514152, 514192

The present invention relates to novel method of reducing microbial infections, especially bacterial infections, of animals, especially of aquatic animals such as fish maintained in tanks or aquaria. The present invention provides bathing and dipping methods for reducing a microbial infection of an animal with an antibiotic solution of enhanced antimicrobial activity comprising at least one chelating agent and at least one antibiotic effective against the microbial infection. The present invention also provides a method for reducing a microbial infection of an animal comprising bathing or dipping an animal having a microbial infection in an antimicrobial solution comprising the chelating agent EDTA, and at least one antibiotic, and optionally a pH buffering agent. The immersion of the aquatic animal in the antimicrobial solution containing the EDTA, antibiotic and pH buffering agent may be repeated until the microbial burden of the animal is eliminated. The present invention further provides kits for use in administering an enhanced activity antibiotic solution.

7785822, Aug 31, 2010

Aug 27, 2003

10/525893

Christopher Gregory - Nicholson GA, US
Branson W. Ritchie - Athens GA, US

University of Georgia Research Foundation, Inc. - Athens GA

C12N 5/07
C12N 5/10
C12Q 1/00

435 25, 435 4, 435349, 435967

The present invention provides methods for the detection of biliverdin in birds (avian species) and reptiles.

20020091074, Jul 11, 2002

Sep 18, 2001

09/955657

Richard Wooley - Athens GA, US
Branson Ritchie - Athens GA, US

A61K031/00
C12Q001/18

514/001000, 435/032000

The present invention relates to methods of inhibiting the proliferation of a microbial population of a surface lesion of a human or animal, wherein the lesion is contacted with an antimicrobial composition comprising a pharmaceutically acceptable antibiotic, a pharmaceutically acceptable chelating agent and a pharmaceutically acceptable pH buffering agent. Another aspect of the present invention is a medical dressing for delivering an antimicrobial composition to a site of a skin injury or lesion of a mammal, comprising a support and an antimicrobial composition, wherein the antimicrobial composition is at least one antimicrobial agent and at least one chelating agent. The present invention also relates to methods for delivering an antibiotic to an injury to the skin of a human or animal and to kits for the preparation and use of an antimicrobial composition to inhibit a microbial infection of a skin injury or lesion of a human or animal.

20040151765, Aug 5, 2004

Dec 18, 2003

10/739841

Branson Ritchie - Athens GA, US
Anthony Capomacchia - Bishop GA, US
Richard Wooley - Athens GA, US

A61K031/573
A61K031/56
A61L015/00

424/445000, 514/179000

The present invention provides methods for wound management that comprise contacting a wound of a patient with an effective amount of a therapeutic composition comprising a chelating agent, a pH buffering agent, an antimicrobial agent, Vitamin E and a carrier and a surfactant. The antimicrobial agent(s) has increased antimicrobial activity because of the synergy with the chelating agent and maintenance of the treated area at a pH suitable for sustained antibiotic activity so that the antimicrobial agent can be used in effective doses that are less than in the absence of the chelator. The Vitamin E promotes tissue repair, reducing the likelihood of opportunistic infection, improving wound healing and reducing pain sensation. The wound management methods of the present invention further include contacting the wound with a medical dressing having an effective amount of the composition deposited thereon. The present invention further provides methods for use of a therapeutic composition a mouth rinse for repairing a wound of the oral mucosa.

20040208842, Oct 21, 2004

Mar 30, 2004

10/812668

Branson Ritchie - Athens GA, US
Douglas Kemp - Watkinsville GA, US

A61K007/075
A61K007/08

424/070210

The present invention provides a skin cleanser comprising a chelating agent, a buffering agent, a carrier and a detergent such as cocamidopropyl betaine and at concentrations that avoid substantial irritation of the skin while having the ability to cleanse the skin surface of contaminants. The compositions are especially useful to cleanse the external ear canal of an animal. The chelating agent has a synergistic effect on the ability of the detergent to loosen cerumen and other contaminants from the skin surface, and also on the antimicrobial and antifungal activity of the detergent, thereby reducing microbial colonization that may develop into a pathological condition if not treated. The present invention provides methods for cleansing a skin surface by using the ccleanser which may include more than one antimicrobial agent to inhibit the proliferation of a single invasive organism, or a mixed population of invasive organisms. The invention also provides kits that have packaging that includes instructions on how to prepare and use the compositions to cleanse the surface of the skin.

20070003508, Jan 4, 2007

Jul 1, 2005

11/173824

Richard Wooley - Athens GA, US
Branson Ritchie - Athens GA, US
Douglas Kemp - Watkinsville GA, US
Anthony Capomacchia - Bishop GA, US
Victoria Burnley - Watkinsville GA, US

A61K 31/195
A61K 8/46

424070240, 514566000

The present invention provides methods and compositions that use the combination of Tris and EDTA to inhibit the growth of microorganisms at the site of a wound or burn, and/or to promote the healing of a wound or burn, and/or to reduce the sensation of pain at the site of a wound or burn. The amount of Tris and EDTA applied to a wound or burn can be selected to achieve one or more of the foregoing effects.

20070185202, Aug 9, 2007

Mar 2, 2005

10/598427

Branson Ritchie - Athens GA, US
Richard Wooley - Athens GA, US
Phillip Moore - Athens GA, US
William Weinstein - Athens GA, US

UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. - Athens GA

A61K 31/195

514561000

The present invention provides methods and compositions for use in the methods for contacting an eye of a patient with an effective amount of a therapeutic composition comprising a pharmaceutically acceptable chelating agent, a pharmaceutically acceptable pH buffering agent and an antimicrobial agent.