Young C Kwon

8318156, Nov 27, 2012

Jul 10, 2007

12/373510

Donald W Landry - New York NY, US
Joanne MacDonald - New York NY, US
Daquan Gao - Louisville KY, US
James H. Woods - Ann Arbor MI, US
Roger K. Sunahara - Ann Arbor MI, US
Diwahar L. Narasimhan - Ann Arbor MI, US
Victor Yang - Ann Arbor MI, US
Mei-Chuan Holden Ko - Ann Arbor MI, US
John J. Tesmer - Ann Arbor MI, US
Tien-Yi Lee - Ann Arbor MI, US
Young Min Kwon - Ann Arbor MI, US

The Trustees of Columbia University in the City of New York - New York NY
The Regents of the University of Michigan - Ann Arbor MI
University of Kentucky Research Foundation - Lexington KY

A61K 38/46
A61K 38/43
C12N 9/16
C12N 9/14
C12P 21/06
C12P 19/34
C07H 21/04

424 946, 424 941, 435196, 435195, 435 691, 435 911, 536 231, 536 232, 530350

Embodiments of the invention disclosed herein generally relate to anti-cocaine therapeutics. Specifically, some embodiments of the invention relate to highly efficient, thermostable, and long-lasting cocaine esterase (CocE) mutants that can protect against the toxic and reinforcing effects of cocaine in subjects. Provided herein are mutant CocE polypeptides displaying thermostable esterase activity. Also provided are methods of treating cocaine-induced conditions in a subject in need via administration of mutant CocE as well as methods for high-throughput screening of candidate esterase polypeptides.

20130136728, May 30, 2013

Nov 14, 2012

13/676324

The Trustees of Columbia University in the City of - New York NY, US
James H. Woods - Ann Arbor MI, US
Roger Sunahara - Ann Arbor MI, US
Diwahar L. Narasimhan - Ann Arbor MI, US
Joanne MacDonald - New York NY, US
Victor Yang - Ann Arbor MI, US
Mei-Chuan Holden Ko - Ann Arbor MI, US
John J. Tesmer - Ann Arbor MI, US
Tien-Yi Lee - Ann Arbor MI, US
Young Min Kwon - Ann Arbor MI, US
Daquan Gao - Louisville KY, US

The Trustees of Columbia University in the City of New York - New York NY

C12N 9/18

424 946, 536 232, 435197

Embodiments of the invention disclosed herein generally relate to anti-cocaine therapeutics. Specifically, some embodiments of the invention relate to highly efficient, thermostable, and long-lasting cocaine esterase (CocE) mutants that can protect against the toxic and reinforcing effects of cocaine in subjects. Provided herein are mutant CocE polypeptides displaying thermostable esterase activity. Also provided are methods of treating cocaine-induced conditions in a subject in need via administration of mutant CocE as well as methods for high-throughput screening of candidate esterase polypeptides.

41505670, Apr 24, 1979

Jun 29, 1978

5/920591

Dusan C. Prevorsek - Morristown NJ
Young D. Kwon - Morristown NJ
Raj K. Sharma - Morristown NJ

Allied Chemical Corporation - Morris Township, Morris County NJ

G01M 1702

73146

By wheel testing two tires having different construction parameters, e. g. different tire cords and measuring the temperatures at a few points within each tire body; and by measurement with a high strain dynamic viscoelastometer, the heat generation rate and dynamic tensile moduli (at various temperatures, strain frequencies and tensions) of the cords and rubber used in each tire are determined, where the values of the exponents "X" in the general equation relating cyclic strain amplitude, S, in the tire cord and in the rubber of each tire vs. the dynamic tensile moduli, E, for cords and rubber, at given temperature can be determined in the form: S. sub. A /S. sub. B=( E. sub. B /E. sub. A). sup. X.

54807069, Jan 2, 1996

Jun 16, 1994

8/260661

Hsin L. Li - Parsippany NJ
Young D. Kwon - Mendham NJ
Dusan C. Prevorsek - Morristown NJ

AlliedSignal Inc. - Morris Township NJ

B32B 512
B32B 700
B27N 900

428113

This invention relates to a fire resistant multilayer complex ballistic resistant article comprising at least one first layer comprised a plurality of flammable fibers a first matrix and at least one second layer which is adjacent to said first layer which comprises a plurality of fire resistant fibers in a second matrix, wherein the second matrix comprises a fire retardant material and is different from the first matrix material.

52601226, Nov 9, 1993

Sep 5, 1991

7/755249

Dusan C. Prevorsek - Morristown NJ
Young D. Kwon - Mendham NJ
Hong B. Chin - Parsippany NJ

Allied-Signal Inc. - Morris Township, Morris County NJ

D03D 300

428225

This invention is related to a woven fibrous article which exhibits relatively low reductions in energy-to-break and tenacity on repeated impacts.

40569730, Nov 8, 1977

Dec 13, 1976

5/750039

Dusan C. Prevorsek - Morristown NJ
Young D. Kwon - Morristown NJ
Raj K. Sharma - Morristown NJ

Allied Chemical Corporation - Morris Township NJ

G01N 334

73 91

An apparatus and method for testing viscoelastic solids, such as tire cord. The apparatus includes: holding means, pretension means, first and second displacement generators, and mechanical-electrical transforming means. The holding means holds the material in a predetermined position. The pretension means applies tension during testing. The first displacement generator has an eccentric means for applying cyclic displacement. The second displacement generator applies cyclic displacement to the material co-directional with that applied by the first displacement generator, but of smaller amplitude and higher frequency. The mechanical-electrical transforming means transforms mechanical motion into electrical signals, such as a stress signal, a strain signal and a differentiated strain signal. The apparatus may also include means for differential testing of duplicate material samples wherein one sample is subjected to cyclic displacement of both the first and second displacement generators, and the other sample is subjected to cyclic displacement of the first displacement generator only. The apparatus may further include integrating means for integration of a stress-strain hysteresis loop.

44407114, Apr 3, 1984

Sep 30, 1982

6/432044

Young D. Kwon - Morristown NJ
Sheldon Kavesh - Whippany NJ
Dusan C. Prevorsek - Morristown NJ

Allied Corporation - Morris Township, Morris County NJ

D01F 614

264185

Polyvinyl alcohol of molecular weight over 500,000 (i. e. 1,500,000 to 2,500,000) is spun as a dilute solution (2-15%) in a relatively non-volatile solvent such as glycerin. The resultant gel fiber is extracted with a volatile solvent such as methanol and dried. Upon stretching at one or more stages during the process, fibers of tenacity above 10 g/denier and modulus above 200 g/denier (e. g. 18 and 450, respectively) are produced.

50063901, Apr 9, 1991

Jun 19, 1989

7/367642

Sheldon Kavesh - Whippany NJ
Kwang Kim - Seoul, KR
Young D. Kwon - Morristown NJ
Dusan C. Prevorsek - Morristown NJ

Allied-Signal - Morris Township, Morris County NJ

B32B 508,12
B32B 2702

428105

The present invention relates to high strength, high modulus polyethylene filaments which form composites having improved shear strength and composites formed from said filaments.