US Patent:
20110250608, Oct 13, 2011
Inventors:
Tushar Patel - Ponte Vedra Beach FL, US
Chiara Braconi - Columbus OH, US
Assignee:
THE OHIO STATE UNIVERSITY - Columbus OH
International Classification:
C12Q 1/68
C07H 21/04
C07H 21/02
G01N 33/53
C12N 15/63
US Classification:
435 614, 436 64, 4353201, 536 245, 536 231
Abstract:
A method of analyzing a biological specimen to detect cancer in a subject, involving determining an ultraconserved RNA in the specimen and comparing the expression level to a control. The ultraconseved RNA may be uc.338 and may be used to detect hepatocellular cancer. Transcript RNA encoding ultraconserved RNA may also be used to detect cancer. Anti-cancer compositions and tumor-suppressing agents for treating cancer are also provided.
