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Christian Dombrowski Phones & Addresses

  • Newtonville, MA
  • Jamaica Plain, MA

Publications

Us Patents

Polynucleotides, Compositions, And Methods For Polypeptide Expression

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US Patent:
20230012687, Jan 19, 2023
Filed:
Sep 27, 2021
Appl. No.:
17/486039
Inventors:
- Cambridge MA, US
Christian Dombrowski - Auburndale MA, US
Seth C. Alexander - Medford MA, US
Assignee:
Intellia Therapeutics, Inc. - Cambridge MA
International Classification:
C12N 15/67
C12N 9/22
C12N 15/90
C12N 15/88
C12N 15/11
Abstract:
Compositions and methods for gene editing. In some embodiments, a polynucleotide encoding Cas9 is provided that can provide one or more of improved editing efficiency, reduced immunogenicity, or other benefits.

Stabilized Nucleic Acids Encoding Messenger Ribonucleic Acid (Mrna)

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US Patent:
20200172564, Jun 4, 2020
Filed:
Feb 14, 2020
Appl. No.:
16/791076
Inventors:
- Cambridge MA, US
Christian Dombrowski - Auburndale MA, US
Assignee:
Intellia Therapeutics, Inc. - Cambridge MA
International Classification:
C07H 21/02
C12N 15/11
C12N 15/63
Abstract:
This disclosure relates to the field of poly-adenylated (poly-A) tails. In some embodiments, a DNA encodes a poly-A tail located 3′ to nucleotides encoding a protein of interest, wherein the poly-A tail comprises one or more non-adenine nucleotide.
Christian Dombrowski from Newtonville, MA, age ~49 Get Report