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David Boczkowski Phones & Addresses

  • 406 Frontgate Dr, Morrisville, NC 27519 (919) 447-0220 (919) 812-4857
  • Cary, NC
  • 4710 Buttonbush Dr, Durham, NC 27712 (919) 477-6407
  • McKeesport, PA
  • Elizabeth, PA
  • Pittsburgh, PA
  • Buena Vista, PA
  • Monongahela, PA
  • Canonsburg, PA
  • 406 Frontgate Dr, Cary, NC 27519

Work

Position: Medical Professional

Education

Degree: High school graduate or higher

Resumes

Resumes

David Boczkowski Photo 1

Associate In Research At Duke University

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Location:
b308 Res Dr, Durham, NC
Industry:
Research
Work:
Duke University Apr 1996 - Apr 1998
Research Analyst Ii

Duke University Apr 1996 - Apr 1998
Associate In Research at Duke University

Duke University Medical Center Apr 1994 - Apr 1996
Research Analyst I

Macronex Dec 1992 - Apr 1994
Research Associate

Central Blood Bank of Pittsburgh Jul 1980 - Dec 1992
Technologist Ii, Supervisor- Patient Transfusion Services and Reference Laboratory
Education:
University of Pittsburgh School of Medicine 1989 - 1992
Masters, Genetics, Biochemistry
University of Pittsburgh 1979 - 1981
Bachelors, Bachelor of Science
Skills:
Pcr
Cell Culture
Research
Molecular Biology
Western Blotting
Molecular Cloning
Laboratory
Life Sciences
Biochemistry
Cell Biology
Tissue Culture
Immunology
Flow Cytometry
Science
Protein Chemistry
David Boczkowski Photo 2

David Boczkowski

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Publications

Us Patents

Method Of Identifying Tumor Antigens That Elicit A T-Cell Response

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US Patent:
6387701, May 14, 2002
Filed:
Apr 30, 1999
Appl. No.:
09/302329
Inventors:
Smita K. Nair - Durham NC
David J. Boczkowski - Durham NC
Eli Gilboa - Durham NC
Assignee:
Duke University - Durham NC
International Classification:
C12N 1509
US Classification:
435455, 435325, 435 71
Abstract:
The present invention relates, in general, to RNA-loaded antigen presenting cells and, in particular, to methods for treating or preventing tumor formation or pathogen infection in a patient. The invention further relates to methods of monitoring T-cell stimulation and to methods of antigen discovery.

Rna-Loaded Antigen Presenting Cells

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US Patent:
6670186, Dec 30, 2003
Filed:
Sep 22, 2000
Appl. No.:
09/667319
Inventors:
Smita K. Nair - Durham NC
David J. Boczkowski - Durham NC
Eli Gilboa - Durham NC
Assignee:
Duke University - Durham NC
International Classification:
C12N 1509
US Classification:
435455, 435325, 435 71
Abstract:
The present invention relates, in general, to RNA-loaded antigen presenting cells and, in particular, to methods for treating or preventing tumor formation or pathogen infection in a patient. The invention further relates to methods of monitoring T-cell stimulation and to methods of antigen discovery.

Methods For Treating Cancers And Pathogen Infections Using Antigen-Presenting Cells Loaded With Rna

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US Patent:
7101705, Sep 5, 2006
Filed:
Jun 7, 2001
Appl. No.:
09/875264
Inventors:
Smita K. Nair - Durham NC, US
David J. Boczkowski - Durham NC, US
Eli Gilboa - Durham NC, US
Assignee:
Duke University - Durham NC
International Classification:
C12N 15/85
US Classification:
435325
Abstract:
Disclosed are cells and methods for treating or preventing tumor formation or infections with pathogens in a patient. The cells of the invention are antigen-presenting cells (e. g. , dendritic cells or macrophage) that have been loaded with RNA derived from tumors or pathogens. By administering the RNA-loaded antigen-presenting cells to a patient, tumor formation or pathogen infections can be treated or prevented. Alternatively, the RNA-loaded cells can be used as stimulator cells in the ex vivo expansion of CTL. Such CTL can then be used in a variation of conventional adoptive immunotherapy techniques.

Methods For Treating Cancers And Pathogen Infections Using Antigen-Presenting Cells Loaded With Rna

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US Patent:
7105157, Sep 12, 2006
Filed:
Apr 30, 1997
Appl. No.:
09/171916
Inventors:
Smita K. Nair - Durham NC, US
David J. Boczkowski - Durham NC, US
Eli Gilboa - Durham NC, US
Assignee:
Duke University - Durham NC
International Classification:
A61K 48/00
C12N 5/10
C12Q 1/68
C12Q 1/70
US Classification:
424 9321, 424 931, 424 932, 435325, 435 5, 435 6, 435 71, 435 72, 435 691, 435455, 435458, 435372, 4353723, 536 231
Abstract:
The present invention relates to cells and methods for treating or preventing tumor formation or infections with pathogens in a patient. The cells of the invention are antigen-presenting cells (e. g. , dendritic cells or macrophage) that have been loaded with RNA derived from tumors or pathogens. By administering the RNA-loaded antigen-presenting cells to a patient, tumor formation or pathogen infections can be treated or prevented. Alternatively, the RNA-loaded cells can be used as stimulator cells in the ex vivo expansion of CTL. Such CTL can then be used in a variation of conventional adoptive immunotherapy techniques.

Methods For Treating Cancers And Pathogen Infections Using Antigen-Presenting Cells Loaded With Rna

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US Patent:
7601343, Oct 13, 2009
Filed:
Oct 17, 2005
Appl. No.:
11/250546
Inventors:
Smita K. Nair - Durham NC, US
David J. Boczkowski - Durham NC, US
Eli Gilboa - Durham NC, US
Assignee:
Duke University - Durham NC
International Classification:
A61K 48/00
C12N 15/85
C12N 5/12
C12N 7/00
US Classification:
424 9321, 435325, 435326
Abstract:
Disclosed are cells and methods for treating or preventing tumor formation or infections with pathogens in a patient. The cells of the invention are antigen-presenting cells (e. g. , dendritic cells or macrophage) that have been loaded with RNA derived from tumors or pathogens. By administering the RNA-loaded antigen-presenting cells to a patient, tumor formation or pathogen infections can be treated or prevented. Alternatively, the RNA-loaded cells can be used as stimulator cells in the ex vivo expansion of CTL. Such CTL can then be used in a variation of conventional adoptive immunotherapy techniques.

Methods For Treating Cancers And Pathogen Infections Using Antigen-Presenting Cells Loaded With Rna

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US Patent:
8263066, Sep 11, 2012
Filed:
Sep 1, 2009
Appl. No.:
12/585028
Inventors:
Smita K. Nair - Durham NC, US
David J. Boczkowski - Durham NC, US
Eli Gilboa - Durham NC, US
Assignee:
Duke University - Durham NC
International Classification:
A61K 35/00
C12N 15/85
US Classification:
424 931, 435325
Abstract:
Disclosed are cells and methods for treating or preventing tumor formation or infections with pathogens in a patient. The cells of the invention are antigen-presenting cells (e. g. , dendritic cells or macrophage) that have been loaded with RNA derived from tumors or pathogens. By administering the RNA-loaded antigen-presenting cells to a patient, tumor formation or pathogen infections can be treated or prevented. Alternatively, the RNA-loaded cells can be used as stimulator cells in the ex vivo expansion of CTL. Such CTL can then be used in a variation of conventional adoptive immunotherapy techniques.

Angio-Immunotherapy

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US Patent:
20040115174, Jun 17, 2004
Filed:
Jul 3, 2003
Appl. No.:
10/613262
Inventors:
Eli Gilboa - Durham NC, US
Smita Nair - Morrisville NC, US
David Boczkowski - Morrisville NC, US
Assignee:
Duke University
International Classification:
A61K039/00
US Classification:
424/093700, 424/184100
Abstract:
The present invention relates, in general, to cancer therapy and, in particular, to a method of treating cancer that involves immunization against an endothelial-specific product preferentially expressed during tumor angiogenesis or against a factor that contributes to the angiogenic process.

Methods For Treating Cancers And Pathogen Infections Using Antigen-Presenting Cells Loaded With Rna

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US Patent:
20120288931, Nov 15, 2012
Filed:
Jul 20, 2012
Appl. No.:
13/554938
Inventors:
Smita K. NAIR - Durham NC, US
David J. Boczkowski - Durham NC, US
Eli Gilboa - Durham NC, US
Assignee:
DUKE UNIVERSITY - Durham NC
International Classification:
C12N 5/10
US Classification:
435325
Abstract:
Disclosed are cells and methods for treating or preventing tumor formation or infections with pathogens in a patient. The cells of the invention are antigen-presenting cells (e.g., dendritic cells or macrophage) that have been loaded with RNA derived from tumors or pathogens. By administering the RNA-loaded antigen-presenting cells to a patient, tumor formation or pathogen infections can be treated or prevented. Alternatively, the RNA-loaded cells can be used as stimulator cells in the ex vivo expansion of CTL. Such CTL can then be used in a variation of conventional adoptive immunotherapy techniques.
David J Boczkowski from Cary, NC, age ~64 Get Report