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David A Hogsett

from Auburn, CA
Age ~58
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Also known as:
Davids A Hogsett, David T
Phone and address:
87 Sylvan Vista Dr, Auburn, CA 95603
(763) 434-7014
Related to:
Evelin C Buker, 85David O Buker, 84
Connected to:
Cheryl Hogsett, 50Jonathan D Hogsett, 38Catherine J Hogsten, 64Chester B Hogston, 66Janet D Hogstrom, 76Paul H Hogu, 67Adrian R Hogue, 46Benjamin C Hogue, 43Brooke R Hogue, 43Caisson T Hogue, 46

David Hogsett Phones & Addresses

  • 87 Sylvan Vista Dr, Auburn, CA 95603 (763) 434-7014
  • Davis, CA
  • Longmont, CO
  • Grantham, NH
  • Hanover, NH
  • Ham Lake, MN
  • Boulder, CO
  • Austin, MN

Work

Company: Novozymes Aug 2015 Position: Science director at novozymes

Education

Degree: Doctorates, Doctor of Philosophy School / High School: Dartmouth College 1988 to 1994 Specialities: Biochemical Engineering

Skills

Biotechnology • Fermentation • Biofuels • Technology Transfer • R&D • Biochemistry • Microbiology • Chromatography • Commercialization • Protein Chemistry • Molecular Biology • Product Development • Protein Purification • Process Simulation • Biopharmaceuticals • Chemistry • Manufacturing • Chemical Engineering • Hplc • Life Sciences • Purification • Research and Development • Laboratory • Protein Expression • Lifesciences • Biochemical Engineering • Gmp • Start Ups • Analytical Chemistry • Spectroscopy • Cell • Metabolic Engineering • Assay Development • Validation • Process Optimization • Pilot Plant • Biomaterials • Biomass • Fermentation Technology • Gas Chromatography • Elisa • Mass Spectrometry

Interests

Science and Technology • Education

Industries

Biotechnology

Resumes

Resumes

David Hogsett Photo 1

Science Director At Novozymes

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Location:
7723 Highland Park Dr, Brownsburg, IN 46112
Industry:
Biotechnology
Work:
Novozymes
Science Director at Novozymes
Opx Biotechnologies Jan 2013 - Apr 2015
Chief Technology Officer, Vice President Research and Development
Mascoma Llc Sep 2006 - Dec 2012
Vice President Research and Development; Vice President External Research and Development
Advanced Bioconversion Technologies Mar 2005 - Sep 2006
President
Bioenergy Jul 1995 - Jun 2005
V.p Research, Development and Manufacturing
Education:
Dartmouth College 1988 - 1994
Doctorates, Doctor of Philosophy, Biochemical Engineering Trinity University 1984 - 1988
Bachelors, Bachelor of Science, Engineering Dartmouth College 1983 - 1985
Doctorates, Doctor of Philosophy
Skills:
Biotechnology
Fermentation
Biofuels
Technology Transfer
R&D
Biochemistry
Microbiology
Chromatography
Commercialization
Protein Chemistry
Molecular Biology
Product Development
Protein Purification
Process Simulation
Biopharmaceuticals
Chemistry
Manufacturing
Chemical Engineering
Hplc
Life Sciences
Purification
Research and Development
Laboratory
Protein Expression
Lifesciences
Biochemical Engineering
Gmp
Start Ups
Analytical Chemistry
Spectroscopy
Cell
Metabolic Engineering
Assay Development
Validation
Process Optimization
Pilot Plant
Biomaterials
Biomass
Fermentation Technology
Gas Chromatography
Elisa
Mass Spectrometry
Interests:
Science and Technology
Education

Business Records

Name / Title
Company / Classification
Phones & Addresses
David Hogsett
Vice President-research And Development
MASCOMA CORPORATION
Alternative Fuels
67 Etna Rd SUITE 300, Lebanon, NH 03766
(617) 234-0099, (603) 676-3320
David Hogsett
President
Symbiora, Inc
Commercial Physical Research
6 Winter Hl, Grantham, NH 03753
PO Box 1107, Grantham, NH 03753

Publications

Us Patents

Gene Knockout Mesophilic And Thermophilic Organisms, And Methods Of Use Thereof

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US Patent:
8435770, May 7, 2013
Filed:
May 9, 2008
Appl. No.:
12/599458
Inventors:
David Anthony Hogsett - Grantham NH, US
Vineet Badriphrajad Rajgarhia - Lebanon NH, US
Assignee:
Mascoma Corporation - Lebanon NH
International Classification:
C12P 7/06
C12N 1/20
C12N 15/00
C07H 21/04
US Classification:
435161, 4352523, 4353201, 536 232
Abstract:
One aspect of the invention relates to a genetically modified thermophilic or mesophilic microorganism, wherein a first native gene is partially, substantially, or completely deleted, silenced, inactivated, or down-regulated, which first native gene encodes a first native enzyme involved in the metabolic production of an organic acid or a salt thereof, thereby increasing the native ability of said thermophilic or mesophilic microorganism to produce ethanol as a fermentation product. In certain embodiments, the aforementioned microorganism further comprises a first non-native gene, which first non-native gene encodes a first non-native enzyme involved in the metabolic production of ethanol. Another aspect of the invention relates to a process for converting lignocellulosic biomass to ethanol, comprising contacting lignocellulosic biomass with a genetically modified thermophilic or mesophilic microorganism.

Thermophilic Organisms For Conversion Of Lignocellulosic Biomass To Ethanol

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US Patent:
20090221049, Sep 3, 2009
Filed:
May 1, 2007
Appl. No.:
12/299070
Inventors:
Sunil G. Desai - Andover MA, US
Lee R. Lynd - Meriden NH, US
Mikhail V. Tyurin - BainBridge GA, US
Kara Podkaminer - Jamesville NY, US
John Bardsley - Cambridge MA, US
David Anthony Hogsett - Grantham NH, US
International Classification:
C12P 7/06
C12N 1/21
C12N 15/11
C12N 15/00
US Classification:
435161, 4352523, 536 231, 4353201
Abstract:
Mutant thermophilic organisms that consume a variety of biomass derived substrates are disclosed herein. Strains of with acetate kinase and phosphotransacetylase expression eliminated are disclosed herein. Further, strain ALK1 has been engineered by site directed homologous recombination to knockout both acetic acid and lactic acid production. Continuous culture involving a substrate concentration challenge lead to evolution of ALK1, and formation of a more robust strain designated ALK2. The organisms may be utilized for example in thermophilic SSF and SSCF reactions performed at temperatures that are optimal for cellulase activity to produce near theoretical ethanol yields without expressing pyruvate decarboxylase.

Microbial Treatment Of Lignocellulosic Biomass

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US Patent:
20110177573, Jul 21, 2011
Filed:
Aug 3, 2009
Appl. No.:
13/055783
Inventors:
Sarah All - White River Junction VT, US
David Anthony Hogsett - Grantham NH, US
International Classification:
C12P 7/06
US Classification:
435161
Abstract:
Aspects of the present invention relate to methods of microbially treating lignocellulosic biomass using cellulose- and/or hemicellulose-degrading bacteria. In certain embodiments, the microbially treated material is then subjected to thermal and/or chemical pretreatment. In tandem with the microbial treatment the thermal and/or chemical pretreatment may result in the production of fewer degradation products, thereby allowing for higher overall yields of ethanol per ton of starting biomass.

Modification Of Hydrogenase Activities In Thermophilic Bacteria To Enhance Ethanol Production

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US Patent:
20110256601, Oct 20, 2011
Filed:
Dec 17, 2008
Appl. No.:
12/808764
Inventors:
Lee Lynd - Meriden NH, US
David A. Hogsett - Grantham NH, US
Assignee:
THE TRUSTEES OF DARTMOUTH COLLEGE - Hanover NH
International Classification:
C12P 7/10
C12N 1/19
C12N 9/02
C12P 7/06
C12N 1/20
C07H 21/04
C12N 1/21
C12N 15/63
US Classification:
435165, 4352523, 4352542, 4353201, 435161, 4352521, 536 237, 435189
Abstract:
Bacteria consume a variety of biomass-derived substrates and produce ethanol. Hydrogenase genes have been inactivated m to generate mutant strains with reduced hydrogenase activities. One such mutant strain with both the ldh and hydtrA genes inactivated shows a significant increase in ethanol production. Manipulation of hydrogenase activities provides a new approach for enhancing substrate utilization and ethanol production by biomass-fermenting microorganisms.

Gene Knockout Mesophilic And Thermophilic Organisms, And Methods Of Use Thereof

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US Patent:
20120094343, Apr 19, 2012
Filed:
Nov 12, 2009
Appl. No.:
13/129085
Inventors:
David A. Hogsett - Grantham NH, US
Vineet Rajgarhia - Lebanon NH, US
Nicky C. Caiazza - Rancho Santa Fe CA, US
Assignee:
Mascoma Corporation - Lebanon NH
International Classification:
C12P 7/56
C12P 7/54
C12N 1/21
C12N 15/11
C12N 15/74
US Classification:
435139, 536 231, 4353201, 4352523, 43525231, 435140
Abstract:
One aspect of the invention relates to a genetically modified thermophilic or mesophilic microorganism, wherein a first native gene is partially, substantially, or completely deleted, silenced, inactivated, or down-regulated, which first native gene encodes a first native enzyme involved in the metabolic production of an organic acid or a salt thereof, thereby increasing the native ability of said thermophilic or mesophilic microorganism to produce lactate or acetate as a fermentation product. In certain embodiments, the aforementioned microorganism further comprises a first non-native gene, which first non-native gene encodes a first non-native enzyme involved in the metabolic production of lactate or acetate. Another aspect of the invention relates to a process for converting lignocellulosic biomass to lactate or acetate, comprising contacting lignocellulosic biomass with a genetically modified thermophilic or mesophilic microorganism.

Production Of Pure Lignin From Lignocellulosic Biomass

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US Patent:
20120108798, May 3, 2012
Filed:
Oct 16, 2009
Appl. No.:
13/124255
Inventors:
Kevin S. Wenger - Hanover NH, US
David A. Hogsett - Grantham NH, US
Michael Ladisch - West Lafayette IN, US
Assignee:
Mascoma Corporation - Lebanon , NH
International Classification:
C08H 7/00
C12S 3/00
US Classification:
530500, 435267
Abstract:
The present invention is directed to a process of producing substantially pure lignin from lignocellulosic biomass, which comprises: pre-treating a lignocellulosic feedstock to produce a reactive lignin-carbohydrate mixture; biologically-reacting the carbohydrates in the mixture, separating remaining solids from the liquid fermentation products, and drying the resulting solids to yield a substantially pure lignin product. Optionally, the lignin product may be washed and subjected to a second hydrolysis step. Optionally, the lignin product may be further processed by hydrotreating and/or pyrolysis in order to yield desirable products such as fuel additives.

Yeast Cells Expressing An Exogenous Cellulosome And Methods Of Using The Same

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US Patent:
20120142046, Jun 7, 2012
Filed:
Feb 18, 2010
Appl. No.:
13/201257
Inventors:
John McBride - Lyme NH, US
Mark Mellon - Grantham NH, US
Vineet Rajgarhia - Dublin CA, US
Elena E. Brevnova - Lebanon NH, US
Erin Wiswall - Danbury NH, US
David A. Hogsett - Grantham NH, US
Danie LaGrange - Durbanville, ZA
Shaunita Rose - Strand, ZA
Emile Van Zyl - Stellenbosch, ZA
International Classification:
C12P 7/10
C12P 39/00
C12N 9/96
C12P 1/00
C12N 1/19
C12N 1/13
US Classification:
435 42, 4352542, 43525421, 43525422, 43525423, 4352572, 435188, 435 41, 435165
Abstract:
The present invention relates to the engineering and expression of heterologous cellulosomes in microorganisms in order to facilitate the conversion of biomass to useful products. In some embodiments, the invention relates to the expression of scaffoldin proteins which form the nucleus of a cellulosome. Cellulases or other biomass-degrading enzymes can be non-covalently linked to the scaffoldin protein by virtue of a dockerin domain-cohesin domain interaction.

Detoxification Of Biomass Derived Acetate Via Metabolic Conversion To Ethanol, Acetone, Isopropanol, Or Ethyl Acetate

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US Patent:
20130273555, Oct 17, 2013
Filed:
May 5, 2011
Appl. No.:
13/696207
Inventors:
William Ryan Sillers - Lebanon NH, US
Hans Van Dijken - Schiedam HG, NL
Steve Licht - Utica NY, US
Alan Benjamin Gilbert - Lebanon NH, US
Aaron Argyros - White River Junction VT, US
Allan C. Froehlich - Lebanon NH, US
John E. McBride - Lyme NH, US
Haowen Xu - Lebanon NH, US
David A. Hogsett - Lebanon NH, US
Vineet B. Rajgarhia - Lebanon NH, US
Assignee:
Mascoma Corporation - Lebanon NH
International Classification:
C12N 15/81
C12N 15/74
C12R 1/865
C12P 7/04
C12P 7/62
C12N 1/16
C12P 7/10
C12P 7/28
US Classification:
435 618, 4352542, 43525421, 43525422, 43525423, 435163, 4352551, 435440, 4352523, 435150, 435157, 435135
Abstract:
One aspect of the invention relates to a genetically modified thermophilic or mesophilic microorganism, wherein a first native gene is partially, substantially, or completely deleted, silenced, inactivated, or down-regulated, which first native gene encodes a first native enzyme involved in the metabolic production of an organic acid or a salt thereof, thereby increasing the native ability of said thermophilic or mesophilic microorganism to produce lactate or acetate as a fermentation product. In certain embodiments, the aforementioned microorganism further comprises a first non-native gene, which first non-native gene encodes a first non-native enzyme involved in the metabolic production of lactate or acetate. Another aspect of the invention relates to a process for converting lignocellulosic biomass to lactate or acetate, comprising contacting lignocellulosic biomass with a genetically modified thermophilic or mesophilic microorganism.
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David A Hogsett from Auburn, CA, age ~58 Get Report