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Edgars Jecs Phones & Addresses

  • Highland Park, IL
  • Waukegan, IL
  • Decatur, GA
  • Amherst, NY
  • Buffalo, NY
  • Hermitage, AR

Resumes

Resumes

Edgars Jecs Photo 1

Edgars Jecs

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Location:
United States

Publications

Us Patents

Inhibitors Of Rsv Replication And Applications Thereof

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US Patent:
20210244740, Aug 12, 2021
Filed:
May 3, 2019
Appl. No.:
17/052595
Inventors:
- Atlanta GA, US
Edgars JECS - Decatur GA, US
Dennis LIOTTA - Atlanta GA, US
Stephen PELLY - Atlanta GA, US
Robert WILSON - Ganesvoort NY, US
Zackery Will DENTMON - East Point GA, US
International Classification:
A61K 31/519
C07D 487/04
C07D 311/18
C07D 311/16
A61P 31/14
A61K 47/60
A61K 31/353
Abstract:
Disclosed herein are compounds having antiviral activity, and, in particular, an inhibitory activity on the replication of Respiratory Syncytial Virus (RSV). Druggable target sites, including Px, in the RSV N protein are disclosed, as well as compounds targeting Px. The compounds can be used to treat patients with RSV infection.

Pan-Tropic Entry Nhibitors

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US Patent:
20210017178, Jan 21, 2021
Filed:
Mar 19, 2019
Appl. No.:
17/040026
Inventors:
- Atlanta GA, US
Edgars Jecs - Decatur GA, US
Yesim Altas Tahirovic - Decatur GA, US
Lawrence Wilson - Chamblee GA, US
Stephen Pelly - Lilburn GA, US
International Classification:
C07D 471/08
C07D 401/14
C07D 401/04
C07D 405/14
Abstract:
This disclosure relates to compounds according to Formula (I), salts, prodrugs and pharmaceutical formulation comprising the compound are provided herein for the treatment of CXCR4 and CCR5 related conditions. The conditions may include viral infections, abnormal cellular proliferation, retinal degeneration and inflammatory diseases, or the compounds may be used as immunostimulants or immunosuppressants. Furthermore, the compounds may be used in combination with another active ingredient selected from an antiviral agent or chemotherapeutic agent.

Chemokine Cxcr4 Receptor Modulators And Uses Related Thereto

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US Patent:
20200054623, Feb 20, 2020
Filed:
Feb 21, 2018
Appl. No.:
16/487825
Inventors:
- Atlanta GA, US
Edgars Jecs - Decatur GA, US
Robert James Wilson - Gansevoort NY, US
Huy Hoang Nguyen - Norcross GA, US
Michelle Bora Kim - Chamblee GA, US
Lawrence Wilson - Atlanta GA, US
Eric James Miller - Atlanta GA, US
Yesim Altas Tahirovic - Atlanta GA, US
Valarie Truax - North Haven CT, US
Thomas Kaiser - Bicester, GB
International Classification:
A61K 31/4725
C07D 401/12
C07D 417/12
C07D 401/14
A61K 31/496
C07D 405/14
C07D 413/14
A61K 31/5377
A61K 31/4995
C07D 487/08
C07D 487/04
A61K 31/4985
C07D 471/04
C07D 417/14
A61K 31/541
A61P 35/00
Abstract:
The disclosure relates to chemokine CXCR4 receptor modulators and uses related thereto. The receptor modulators can be formulated to form pharmaceutical compositions comprising the disclosed compounds or pharmaceutically acceptable salts or prodrugs thereof. The compositions may be used for managing CXCR4 related conditions, typically prevention or treatment of viral infections abnormal cellular proliferation, retinal degeneration, inflammatory diseases, or as an immunostimulant or immunosuppressant or for managing cancer and may be administered with another active ingredient such as an antiviral agent or chemotherapeutic agent.
Edgars Jecs from Highland Park, IL, age ~38 Get Report