Resumes
Resumes
Elmer Pfefferkorn Phones & Addresses
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24 Rope Ferry Rd, Hanover, NH 03755 (603) 643-4458
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Shelbyville, TN
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Tullahoma, TN
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80 Lyme Rd APT 415, Hanover, NH 03755 (603) 643-4458
Publications
Us Patents
Method For The Immunization Of Animals And Men Against Toxoplasma Gondii _
View pageUS Patent:
44735499, Sep 25, 1984
Filed:
Jul 30, 1982
Appl. No.:
6/403787
Inventors:
Jacob K. Frenkel - Overland Park KS
Elmer R. Pfefferkorn - Hanover NH
Elmer R. Pfefferkorn - Hanover NH
Assignee:
The Kansas University Endowment Association
International Classification:
A61K 39002
US Classification:
424 88
Abstract:
A method for the immunization of mammals (including man) and birds, against Toxoplasma gondii is described which involves subcutaneous administration of a live, low-virulent vaccine comprising a temperature-sensitive mutant of the persistent, virulent RH strain of T. gondii. The vaccine gives immunity against subsequent challenge, but does not persist and does not cause chronic infection of the subject and which therefore cannot result in illness or death in the event that the subject later becomes immunosuppressed.
Vaccine For Immunizing Cats Against Toxoplasma Oocyst Shedding
View pageUS Patent:
50453130, Sep 3, 1991
Filed:
Jul 7, 1989
Appl. No.:
7/376809
Inventors:
Jacob K. Frenkel - Overland Park KS
Elmer R. Pfefferkorn - Hanover NH
Elmer R. Pfefferkorn - Hanover NH
Assignee:
The University of Kansas - Lawrence KS
Darmouth College - Hanover NH
Darmouth College - Hanover NH
International Classification:
A61K 3900
C12N 1500
C12N 1500
US Classification:
424 88
Abstract:
A new mutant strain vaccine, and a corresponding method of immunization, against Toxoplasma in cats is provided which makes use of a reproductively deficient strain of T. gondii, designated T-263. Bradyzoites in tissue cysts from laboratory animals infected with the mutant were fed to cats, which developed immunity against subsequent T. gondii challenge without concomitant shedding of infectious oocysts. The new vaccine eliminates the need for chemoprophylaxis subsequent to primary infection.