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Harold C Kluender

from Hartland, WI
Age ~80

Harold Kluender Phones & Addresses

  • 788 Hawthorne Ln, Hartland, WI 53029 (262) 369-0803
  • 27 Academy Rd, Trumbull, CT 06611 (203) 459-0839
  • West Haven, CT
  • South Bend, IN
  • Stevensville, MI
  • Waukesha, WI

Work

Company: Wisconsin lutheran college Aug 2007 Address: Milwaukee, Wisconsin Position: Adjunct instructor - chemistry

Education

Degree: BS,MS,PhD, Post Doc School / High School: UW-Stephens Point, UW-Madison, Wesleyan U - Middletown, CT, Harvard U. 1962 to 1973 Specialities: Chemistry, Organic Chemistry, Math

Skills

Chromatography • Laboratory • Drug Design • Cell Biology • Chemistry • Hplc • Organic Synthesis • Teaching • Biotechnology • Life Sciences • Cell Culture • Purification • Characterization • Drug Discovery • Lifesciences • Organic Chemistry • Oncology • Pharmaceuticals • Clinical Development • Cancer • Medicinal Chemistry • Protein Purification • Research • Pharmaceutical Industry • Science • Biochemistry • Chemdraw • Patents

Languages

German • English

Interests

Early American Coppers (Eac) • Us Large Cent Attribution and Collection • Trout Unlimited • Kayak Fishing • Woodworking

Emails

Industries

Higher Education

Resumes

Resumes

Harold Kluender Photo 1

Harold Kluender

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Location:
788 Hawthorne Ln, Hartland, WI 53029
Industry:
Higher Education
Work:
Wisconsin Lutheran College - Milwaukee, Wisconsin since Aug 2007
Adjunct Instructor - Chemistry

Bayer Healthcare, Pharmaceuticals 1995 - 2006
principal Staff scientist

Valley Coins 1971 - 2006
Retired Scientist and Coin Collector

Miles Laboratories 1973 - 1995
Senior Research Scientist

Bayer - Wuppertal, Germany Jan 1987 - Dec 1988
International Delegate
Education:
UW-Stephens Point, UW-Madison, Wesleyan U - Middletown, CT, Harvard U. 1962 - 1973
BS,MS,PhD, Post Doc, Chemistry, Organic Chemistry, Math
Skills:
Chromatography
Laboratory
Drug Design
Cell Biology
Chemistry
Hplc
Organic Synthesis
Teaching
Biotechnology
Life Sciences
Cell Culture
Purification
Characterization
Drug Discovery
Lifesciences
Organic Chemistry
Oncology
Pharmaceuticals
Clinical Development
Cancer
Medicinal Chemistry
Protein Purification
Research
Pharmaceutical Industry
Science
Biochemistry
Chemdraw
Patents
Interests:
Early American Coppers (Eac)
Us Large Cent Attribution and Collection
Trout Unlimited
Kayak Fishing
Woodworking
Languages:
German
English

Publications

Us Patents

Preparation And Use Of 1,5,6,7-Tetrahydropyrrolo[3,2-C]Pyridine Derivatives For Treatment Of Obesity

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US Patent:
7071207, Jul 4, 2006
Filed:
Sep 24, 2002
Appl. No.:
10/487976
Inventors:
Roger A. Smith - Madison CT, US
Stephen J. O'Connor - Guilford CT, US
Wai C. Wong - Trumbull CT, US
Soongyu Choi - Skillman NJ, US
Harold C. Kluender - Trumbull CT, US
Jianmei Fan - Hamden CT, US
Zhonghua Zhang - Derby CT, US
Rico C. Lavoie - Chesire CT, US
Brent L. Podlogar - Flemington NJ, US
Assignee:
Bayer Pharmaceuticals Corporation - West Haven CT
International Classification:
A61K 31/40
A61K 31/395
A61K 31/437
C07D 471/04
C07D 471/14
US Classification:
514300, 514318, 514333, 546113, 5462767, 546289
Abstract:
This invention relates to 1,5,6,7-tetrahydropyrrolo[3,2-c]pyridine derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.

Substituted 4-Amino-Pyrrolotriazine Derivatives Useful For Treating Hyper-Proliferative Disorders And Diseases Associated With Angiogenesis

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US Patent:
8133995, Mar 13, 2012
Filed:
Nov 30, 2006
Appl. No.:
12/085879
Inventors:
Julie Dixon - Bethany CT, US
Steven Magnuson - Wallingford CT, US
Barton Phillips - New Haven CT, US
Yamin Wang - Sandy Hook CT, US
Tandy Li - West Haven CT, US
Kyle Parcella - Wallingford CT, US
Jason Newcom - Northford CT, US
Harold Kluender - Hartland WI, US
Zhenqiu Hong - Milford CT, US
Brent Chandler - Princeton NJ, US
Zhonghua Zhang - Derby CT, US
Kristen Allegue - Rocky Hill CT, US
Zheng Liu - Beacon Falls CT, US
Assignee:
Bayer HealthCare LLC - Tarrytown NY
International Classification:
C07D 487/04
C07D 417/02
C07D 413/02
A61K 31/53
A61P 35/00
US Classification:
544183, 514243
Abstract:
This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.

Substituted 2-Arylimino Heterocycles And Compositions Containing Them For Use As Progesterone Receptor Binding Agents

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US Patent:
20030207865, Nov 6, 2003
Filed:
Oct 23, 2001
Appl. No.:
10/004306
Inventors:
Brian Dixon - Woodbridge CT, US
Cedo Bagi - Branford CT, US
Catherine Brennan - Milford CT, US
David Brittelli - Branford CT, US
William Bullock - Easton CT, US
Jinshan Chen - Hamden CT, US
William Collibee - Bethany CT, US
Robert Dally - East Haven CT, US
Jeffrey Johnson - Branford CT, US
Harold Kluender - Trumbull CT, US
William Lathrop - Plantsville CT, US
Peiying Liu - Madison CT, US
Carol Mase - Ringoes NJ, US
Aniko Redman - Derby CT, US
William Scott - Guilford CT, US
Klaus Urbahns - Wuppertal DE, US
Donald Wolanin - Orange CT, US
International Classification:
A61K031/551
A61K031/55
C07D417/02
C07D413/02
C 07D 4 3/02
US Classification:
514/218000, 514/217040, 514/217060, 514/217090, 514/227800, 514/235800, 514/269000, 540/492000, 540/601000, 540/602000, 544/123000, 544/313000, 544/060000
Abstract:
This invention relates to 2-arylimino heterocycles, including 2-arylimino-1,3-thiazolidines, 2-arylimino-2,3,4,5-tetrahydro-1,3-thiazines, 2-arylimino-1,3-thiazolidin-4-ones, 2-arylimino-1,3-thiazolidin-5-ones, and 2-arylimino-1,3-oxazolidines, and their use in modulating progesterone receptor mediated processes, and pharmaceutical compositions for use in such therapies.

Cyclic And Acyclic Amidines And Pharmaceutical Compositions Containing Them For Use As Progesterone Receptor Binning Agents

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US Patent:
20030229072, Dec 11, 2003
Filed:
Mar 3, 2003
Appl. No.:
10/363621
Inventors:
William Bullock - Easton CT, US
Harold Kluender - Trumbull CT, US
William Collibee - Bethany CT, US
Robert Dally - Indianapolis IN, US
Martha Rodriguez - Indianapolis CO, US
Ming Wang - Milford CT, US
International Classification:
A61K031/55
A61K031/537
A61K031/4747
A61K031/44
C07D209/54
C07D215/38
US Classification:
514/214010, 540/605000, 540/598000, 546/016000, 546/159000, 540/576000, 548/408000, 564/244000, 540/609000, 544/162000, 546/229000, 514/217120, 514/217110, 514/237800, 514/317000, 514/278000, 514/409000, 514/524000, 514/637000, 514/313000
Abstract:
Disclosed are cyclic and acyclic amidines, pharmaceutical compositions containing such amidines, and their use in treating or preventing progesterone receptor mediated diseases or conditions, such as osteopenia and osteoporosis.

Preparation And Use Of Imidazole Derivatives For Treatment Of Obesity

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US Patent:
20040063691, Apr 1, 2004
Filed:
Sep 24, 2002
Appl. No.:
10/255049
Inventors:
Roger Smith - Madison CT, US
Stephen O'Connor - Guilford CT, US
Stephan-Nicholas Wirtz - Wuppertal, DE
Wai Wong - Hamden CT, US
Soongyu Choi - Trumbull CT, US
Harold Kluender - Trumbull CT, US
Ning Su - Hamden CT, US
Gan Wang - Wallingford CT, US
Furahi Achebe - West Haven CT, US
Shihong Ying - Orange CT, US
International Classification:
C07D417/02
C07D413/02
C 07D 4 3/02
A61K031/55
A61K031/541
A61K031/496
A61K031/5377
A61K031/4168
US Classification:
514/217090, 514/227800, 514/254050, 514/255050, 514/256000, 514/235800, 514/326000, 514/397000, 544/060000, 544/405000, 544/333000, 544/139000, 546/210000, 548/314700, 540/603000
Abstract:
This invention relates to substituted imidazole derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.

Substituted Pyridines And Pyridazines With Angiogenesis Inhibiting Activity

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US Patent:
20040092740, May 13, 2004
Filed:
Nov 24, 2003
Appl. No.:
10/720702
Inventors:
Jacques Dumas - Bethany CT, US
Stephen Boyer - Hilden, DE
Julie Dixon - Bethany CT, US
Teddy Joe - San Francisco CA, US
Harold Kluender - Trumbull CT, US
Wendy Lee - Hamden CT, US
Dhanapalan Nagarathnam - Bethany CT, US
Robert Sibley - North Haven CT, US
Ning Su - Hamden CT, US
Assignee:
Bayer Pharmaceuticals Corporation - West Haven CT
International Classification:
C07D487/02
C 07D 4 3/02
US Classification:
544/236000, 544/238000
Abstract:
Substituted and pyridines and pyridazines having angiogenesis inhibiting activity and the generalized structural formula wherein the ring containing A, B, D, E, and L is phenyl or a nitrogen-containing heterocycle; groups X and Y may be any of a variety of defined linking units; Rand Rmay be defined independent substituents or together may be a ring-defining bridge; ring J may be an aryl, pyridyl, or cycloalkyl group; and G groups may be any of a variety of defined substituents. Pharmaceutical compositions containing these materials, and methods of treating a mammal having a condition characterized by abnormal angiogenesis or hyperpermiability processes using these materials are also disclosed.

Pyrazole Derivatives Useful In The Treatment Of Hyper-Proliferative Disorders

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US Patent:
20040180891, Sep 16, 2004
Filed:
Mar 15, 2004
Appl. No.:
10/489796
Inventors:
Uday Khire - Hamden CT, US
Chengzhi Zhang - Orange CT, US
Harold Kluender - Trumbull CT, US
Ingo Mugge - New Haven CT, US
Jianxing Shao - Cheshire CT, US
Neil Bifulco - Durham NC, US
Pamela Trail - Madison CT, US
Jacques Dumas - Bethany CT, US
Rico Lavoie - Hamden CT, US
Veena Agarwal - Milford CT, US
Sharad Verma - New Haven CT, US
Lei Wang - New Haven CT, US
International Classification:
A61K031/5377
A61K031/4439
A61K031/4152
C07D413/02
C 07D 4 3/02
US Classification:
514/235500, 514/341000, 514/406000, 544/140000, 546/276400, 548/366100
Abstract:
This invention relates to pyrazole derivatives of that are useful for treating hyper-proliferative disorders and angiogenesis dependent disorders.

Preparation And Use Of Pyrrole Derivatives For Treating Obesity

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US Patent:
20040267028, Dec 30, 2004
Filed:
Mar 5, 2004
Appl. No.:
10/489031
Inventors:
Roger Smith - Madison CT, US
Harold Kluender - Trumbull CT, US
Ning Su - Hamden CT, US
Rico Lavoie - Hamden CT, US
Jianmei Fan - Hamden CT, US
International Classification:
C 07D 2 7/335
US Classification:
548/537000
Abstract:
This invention relates to pyrrole derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.
Harold C Kluender from Hartland, WI, age ~80 Get Report