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Jay Theroff Phones & Addresses

  • 2707 Driftwood Dr, Manvel, TX 77578 (832) 637-7166
  • 914 South Ave, Clifton Heights, PA 19018
  • 1250 Providence Rd, Clifton Heights, PA 19018 (610) 328-2728
  • Secane, PA
  • 9 Patrick Ave, West Chester, PA 19380 (610) 719-8116
  • Venetia, PA
  • Chester, PA
  • New Castle, DE
  • University Park, PA
  • Montgomery, TX
  • 2707 Driftwood Dr, Manvel, TX 77578

Work

Position: Food Preparation and Serving Related Occupations

Education

Degree: Bachelor's degree or higher

Publications

Us Patents

Pyridopyrazines And Derivatives Thereof As Alk And C-Met Inhibitors

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US Patent:
7919502, Apr 5, 2011
Filed:
Sep 24, 2009
Appl. No.:
12/566362
Inventors:
Bruce D. Dorsey - Ambler PA, US
Douglas A. Pippin - Chester Springs PA, US
Jay P. Theroff - West Chester PA, US
Craig A. Zificsak - Downingtown PA, US
Assignee:
Cephalon, Inc. - Frazer PA
International Classification:
A61K 31/4375
US Classification:
514300, 546122
Abstract:
The present invention provides a compound of Formula I.

Pyridopyrazines And Derivatives Thereof As Alk And C-Met Inhibitors

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US Patent:
8080561, Dec 20, 2011
Filed:
Feb 25, 2011
Appl. No.:
13/035022
Inventors:
Bruce D. Dorsey - Ambler PA, US
Jay P. Theroff - West Chester PA, US
Linda Weinberg - King of Prussia PA, US
Craig A. Zificsak - Downingtown PA, US
Assignee:
Cephalon, Inc. - Frazer PA
International Classification:
A61K 31/4375
US Classification:
514300, 546122
Abstract:
The present invention provides a compound of Formula I.

Fused Bicyclic Derivatives Of 2,4-Diaminopyrimidine As Alk And C-Met Inhibitors

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US Patent:
8148391, Apr 3, 2012
Filed:
Oct 23, 2007
Appl. No.:
12/162851
Inventors:
Gulzar Ahmed - Voorhees NJ, US
Henry Joseph Breslin - Lansdale PA, US
Jason Burke - Charlottesville VA, US
Matthew A. Curry - Coatesville PA, US
James L. Diebold - Eagleville PA, US
Bruce Dorsey - Ambler PA, US
Benjamin J. Dugan - Glen Mills PA, US
Daming Feng - East Windsor NJ, US
Diane E. Gingrich - Downingtown PA, US
Tao Guo - Dayton NJ, US
Keith S. Learn - Perkiomenville PA, US
Joseph G. Lisko - Glenmoore PA, US
Eugen Florin Mesaros - Philadelphia PA, US
Karen Milkiewicz - Exton PA, US
Gregory R. Ott - Media PA, US
Jay P. Theroff - West Chester PA, US
Tho V. Thieu - Ambler PA, US
Rabindranath Tripathy - Churchville PA, US
Theodore L. Underiner - Malvern PA, US
Gregory J. Wells - West Chester PA, US
Craig A. Zificsak - Downingtown PA, US
Assignee:
Cephalon, Inc. - Frazer PA
International Classification:
A61K 31/505
C07D 239/02
US Classification:
514275, 544330
Abstract:
The present invention provides a compound of formula I or II or a pharmaceutically acceptable salt form thereof, wherein R, R, R, R, R, A, A, A, A, and A, are as defined herein. The compounds of formula I or II have ALK and/or c-Met inhibitory activity, and may be used to treat proliferative disorders.

Pyrrolotriazines As Alk And Jak2 Inhibitors

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US Patent:
8471005, Jun 25, 2013
Filed:
Jun 15, 2011
Appl. No.:
13/160890
Inventors:
Henry J. Breslin - Lansdale PA, US
Sankar Chatterjee - Wynnewood PA, US
James L. Diebold - Eagleville PA, US
Bruce D. Dorsey - Ambler PA, US
Derek D. Dunn - Coatesville PA, US
Diane E. Gingrich - Downingtown PA, US
Greg A. Hostetler - Newark DE, US
Robert L. Hudkins - Chester Springs PA, US
Rachael Hunter - Media PA, US
Kurt A. Josef - Radnor PA, US
Joseph Lisko - Alpharetta GA, US
Eugen F. Mesaros - Wallingford PA, US
Karen L. Milkiewicz - Exton PA, US
Gregory R. Ott - Media PA, US
Babu G. Sundar - West Chester PA, US
Jay P. Theroff - West Chester PA, US
Tho Thieu - Ambler PA, US
Rabindranath Tripathy - Churchville PA, US
Theodore L. Underiner - Malvern PA, US
Linda Weinberg - King of Prussia PA, US
Gregory J. Wells - West Chester PA, US
Craig A. Zificsak - Downingtown PA, US
Assignee:
Cephalon, Inc. - Frazer PA
International Classification:
C07D 487/04
C07D 403/12
A61K 31/53
A61K 31/5377
A61P 35/00
US Classification:
544183, 514243
Abstract:
The present invention provides a compound of formula I.

Fused Bicyclic Derivatives Of 2,4-Diaminopyrimidine As Alk And C-Met Inhibitors

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US Patent:
8552186, Oct 8, 2013
Filed:
Mar 6, 2012
Appl. No.:
13/413322
Inventors:
Gulzar Ahmed - Voorhees NJ, US
Henry J. Breslin - Lansdale PA, US
Jason Burke - Charlottesville VA, US
Matthew A. Curry - Coatesville PA, US
James L. Diebold - Eagleville PA, US
Bruce D. Dorsey - Ambler PA, US
Benjamin J. Dugan - Glen Mills PA, US
Daming Feng - East Windsor NJ, US
Diane E. Gingrich - Downingtown PA, US
Tao Guo - Dayton NJ, US
Keith S. Learn - Perkiomenville PA, US
Joseph Lisko - Alpharetta GA, US
Eugen F. Mesaros - Wallingford PA, US
Karen L. Milkiewicz - Exton PA, US
Gregory R. Ott - Media PA, US
Jay P. Theroff - West Chester PA, US
Tho Thieu - Ambler PA, US
Rabindranath Tripathy - Churchville PA, US
Theodore L. Underiner - Malvern PA, US
Gregory J. Wells - West Chester PA, US
Craig A. Zificsak - Downingtown PA, US
Assignee:
Cephalon, Inc. - Frazier PA
International Classification:
C07D 403/12
US Classification:
544324
Abstract:
The present invention provides a compound of formula I or II.

Pyridopyrazines And Derivatives Thereof As Alk And C-Met Inhibitors

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US Patent:
20080032972, Feb 7, 2008
Filed:
Apr 30, 2007
Appl. No.:
11/799066
Inventors:
Bruce Dorsey - Ambler PA, US
Karen Milkiewicz - Exton PA, US
Douglas Pippin - Chester Springs PA, US
Jay Theroff - West Chester PA, US
Ted Underiner - Malvern PA, US
Linda Weinberg - Villanova PA, US
Craig Zificsak - Downingtown PA, US
Assignee:
Cephalon, Inc. - Frazer PA
International Classification:
A61K 31/4985
A61K 31/5375
A61P 43/00
C07D 413/14
C07D 487/04
US Classification:
514234200, 514250000, 544117000, 544350000
Abstract:
The present invention provides a compound of Formula I or a pharmaceutically acceptable salt form thereof, wherein A, L, R, R, R, R, R, R, and X are as defined herein. The compounds of Formula I have ALK and/or c-Met inhibitory activity, and may be used to treat ALK- or c-Met-mediated disorders or conditions.

Heterocyclic Modulators Of Hif Activity For Treatment Of Disease

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US Patent:
20140066424, Mar 6, 2014
Filed:
Aug 23, 2013
Appl. No.:
13/974258
Inventors:
Maria Emilia DiFrancesco - Houston TX, US
Alessia Petrocchi - Houston TX, US
Christopher L. Carroll - Houston TX, US
Joe Marszalek - Houston TX, US
Barbara Czako - Houston TX, US
Ryan Johnson - Houston TX, US
Jay Theroff - Houston TX, US
Assignee:
Institute For Applied Cancer Science/The University of Texas MD Anderson Cancer Center - Houston TX
International Classification:
C07D 413/04
C07D 417/14
A61K 31/454
A61K 45/06
A61K 31/496
C07D 413/14
C07D 417/04
US Classification:
51421018, 5142362, 51425403, 5142531, 514256, 514274, 514275, 514340, 514364, 514365, 514374, 544137, 544138, 544316, 544331, 544333, 544364, 544367, 544369, 5462691, 548124, 548131, 548205, 548235, 546176, 546194, 514314, 514318
Abstract:
The present invention relates to compounds and methods which may be useful as inhibitors of HIF pathway activity for the treatment or prevention of cancer and other hypoxia-mediated diseases.

Heterocyclic Inhibitors Of Tyrosine Kinase

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US Patent:
20220194940, Jun 23, 2022
Filed:
Apr 24, 2020
Appl. No.:
17/604900
Inventors:
- Austin TX, US
Jacqulyne ROBICHAUX - Manvel TX, US
Monique NILSSON - Sugar Land TX, US
Philip JONES - Houston TX, US
Jason CROSS - Pearland TX, US
Jay THEROFF - Manvel TX, US
International Classification:
C07D 471/04
Abstract:
The present disclosure relates to heterocyclic compounds and methods which may be useful as inhibitors of HER2 or EGFR for the treatment or prevention of disease, including cancer.
Jay P Theroff from Manvel, TX, age ~50 Get Report