Jerome S Luloff

39592766, May 25, 1976

Nov 26, 1974

5/527364

Jerome S. Luloff - Bloomington MN
Albert L. Eilender - Flanders NJ

Cosan Chemical Corporation - Clifton NJ

C07D25104

2602485

A number of water-soluble, one-to-one quaternary ammonium adducts of unsaturated organic halides and dihalides with hexamethylenetetramine are known as being useful as antimicrobial agents. It has not been discovered that a two-to-one quaternary ammonium adduct can be prepared from hexamethylenetetramine and 3,4-dichlorobutene-1; this two-to-one adduct is a more active, less toxic antimicrobial agent than the known one-to-one quaternary ammonium adducts.

RE298832, Jan 16, 1979

May 25, 1977

5/800480

Jerome S. Luloff - Bloomington MN
Albert L. Eilender - Flanders NJ

Cosan Chemical Corporation - Clifton NJ

C07D25104

544186

A number of water-soluble, one-to-one quaternary ammonium adducts of unsaturated organic halides and dihalides with hexamethylenetetramine are known as being useful as antimicrobial agents. It has now been discovered that a two-to-one quaternary ammonium adduct can be prepared from hexamethylenetetramine and 3,4-dichlorobutene-1; this two-to-one adduct is a more active, less toxic antimicrobial agent than the known one-to-one quaternary ammonium adducts.