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Jin She

from Chapel Hill, NC
Age ~51

Jin She Phones & Addresses

  • 133 Vintage Dr, Chapel Hill, NC 27516 (919) 967-9634
  • Carrboro, NC
  • 104 Juliette Ct, Chapel Hill, NC 27516

Work

Position: Clerical/White Collar

Education

Degree: High school graduate or higher

Publications

Wikipedia

Jin Xing

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Although usually credited as Jing Xing, the proper pinyin spelling is Jin Xing. She is one of the first few transgender women officially recognised by the ...

Us Patents

Process For The Preparation Of 3,4-Disubstituted-Thiazolidin-2-Ones

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US Patent:
7414137, Aug 19, 2008
Filed:
Mar 22, 2007
Appl. No.:
11/690048
Inventors:
Jonathan B. DeCamp - Raleigh NC, US
Paul S. Watson - Carrboro NC, US
Jin She - Chapel Hill NC, US
Assignee:
Inspire Pharmaceuticals, Inc. - Durham NC
International Classification:
C07D 277/56
US Classification:
548188
Abstract:
The present invention is directed to practical high-yielding synthetic processes for preparing 3,4-disubstituted-thiazolidin-2-ones, which do not compromise the absolute stereochemical integrity of the compounds. The present invention is also directed to novel compounds of 3,4-disubstituted-thiazolidin-2-ones. The compounds prepared by the present invention are useful in the synthesis and manufacture of compounds (such as latrunculins and/or their analogs) for treating diseases or conditions associated with inhibiting actin polymerization.

Cytoskeletal Active Compounds, Composition And Use

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US Patent:
7666861, Feb 23, 2010
Filed:
Dec 4, 2007
Appl. No.:
11/950327
Inventors:
John W. Lampe - Cary NC, US
Robert Plourde, Jr. - Chapel Hill NC, US
Jin She - Chapel Hill NC, US
Jason L. Vittitow - Durham NC, US
Paul S. Watson - Carrboro NC, US
Michael T. Crimmins - Chapel Hill NC, US
David J. Slade - Durham NC, US
Assignee:
Inspire Pharmaceuticals, Inc. - Durham NC
International Classification:
A61K 31/351
A61K 31/357
C07D 309/06
C07D 313/02
C07D 313/16
US Classification:
51421109, 514450, 540451, 540456, 540468, 548182
Abstract:
The present invention is directed to synthetic cytoskeletal active compounds that are related to natural Latrunculin A or Latrunculin B. The present invention is also directed to pharmaceutical compositions comprising such compounds and a pharmaceutically acceptable carrier. The invention is additionally directed to a method of preventing or treating diseases or conditions associated with actin polymerization. In one embodiment of the invention, the method treats increased intraocular pressure, such as primary open-angle glaucoma. The method comprises administering to a subject a therapeutically effective amount of a cytoskeletal active compound of Formula I or II, wherein said amount is effective to influence the cytoskeleton, for example by inhibiting actin polymerization.

Process For The Preparation Of 3,4-Disubstituted-Thiazolidin-2-Ones

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US Patent:
7947850, May 24, 2011
Filed:
Jul 30, 2008
Appl. No.:
12/182918
Inventors:
Jonathan B. DeCamp - Raleigh NC, US
Paul S. Watson - Carrboro NC, US
Jin She - Chapel Hill NC, US
Assignee:
Inspire Pharmaceuticals, Inc. - Durham NC
International Classification:
C07C 323/58
US Classification:
562426, 548201
Abstract:
The present invention is directed to practical high-yielding synthetic processes for preparing 3,4-disubstituted-thiazolidin-2-ones, which do not compromise the absolute stereochemical integrity of the compounds. The present invention is also directed to novel compounds of 3,4-disubstituted-thiazolidin-2-ones. The compounds prepared by the present invention are useful in the synthesis and manufacture of compounds (such as latrunculins and/or their analogs) for treating diseases or conditions associated with inhibiting actin polymerization.

Cytoskeletal Active Compounds, Composition And Use

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US Patent:
8039465, Oct 18, 2011
Filed:
Jan 28, 2010
Appl. No.:
12/695348
Inventors:
John W. Lampe - Cary NC, US
Robert Plourde, Jr. - Chapel Hill NC, US
Jin She - Chapel Hill NC, US
Jason L. Vittitow - Durham NC, US
Paul S. Watson - Carrboro NC, US
Michael T. Crimmins - Chapel Hill NC, US
David J. Slade - Durham NC, US
Assignee:
Inspire Pharmaceuticals, Inc. - Whitehouse Station NJ
International Classification:
A61K 31/54
US Classification:
5142272, 544122, 544123
Abstract:
The present invention is directed to synthetic cytoskeletal active compounds that are related to natural Latrunculin A or Latrunculin B. The present invention is also directed to pharmaceutical compositions comprising such compounds and a pharmaceutically acceptable carrier. The invention is additionally directed to a method of preventing or treating diseases or conditions associated with actin polymerization. In one embodiment of the invention, the method treats increased intraocular pressure, such as primary open-angle glaucoma. The method comprises administering to a subject a therapeutically effective amount of a cytoskeletal active compound of Formula I or II, wherein said amount is effective to influence the cytoskeleton, for example by inhibiting actin polymerization.

Cytoskeletal Active Compounds, Compositions And Use

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US Patent:
20060217427, Sep 28, 2006
Filed:
Mar 23, 2006
Appl. No.:
11/389665
Inventors:
John Lampe - Cary NC, US
Robert Plourde - Chapel Hill NC, US
Jin She - Chapel Hill NC, US
Jason Vittitow - Durham NC, US
Paul Watson - Carrboro NC, US
Michael Crimmins - Chapel Hill NC, US
David Slade - Durham NC, US
International Classification:
A61K 31/426
A61K 31/422
A61K 31/4178
C07D 413/02
C07D 417/02
C07D 405/02
US Classification:
514369000, 514376000, 514389000, 548182000, 548229000, 548311100
Abstract:
The present invention is directed to synthetic cytoskeletal active compounds that are related to natural Latrunculin A or Latrunculin B. The present invention is also directed to pharmaceutical compositions comprising such compounds and a pharmaceutically acceptable carrier. The invention is additionally directed to a method of preventing or treating diseases or conditions associated with actin polymerization. In one embodiment of the invention, the method treats increased intraocular pressure, such as primary open-angle glaucoma. The method comprises administering to a subject a therapeutically effective amount of a cytoskeletal active compound of Formula I or II, wherein said amount is effective to influence the cytoskeleton, for example by inhibiting actin polymerization.
Jin She from Chapel Hill, NC, age ~51 Get Report