Kenneth A Marby

20040058880, Mar 25, 2004

Jun 26, 2003

10/606700

Kenneth Marby - San Diego CA, US
David Rabuka - San Diego CA, US
Alex Romero - San Diego CA, US
Paul Sgarbi - Richmond, CA
Steven Sucheck - San Diego CA, US
Youe-Kong Shue - Carlsbad CA, US
Sulan Yao - San Diego CA, US

C07H005/06
A61K031/704
A61K031/35

514/036000, 514/042000, 514/459000, 514/460000, 536/018700, 549/416000, 549/419000

This invention relates to novel aminoglycoside compounds having antibacterial and anti-infective activity and to pharmaceutical compositions, methods of making and methods of treatment employing the same.

20060100164, May 11, 2006

Mar 5, 2004

10/548698

Jonathan Duffield - San Diego CA, US
Alex Romero - San Diego CA, US
Yu-Hung Chiu - San Diego CA, US
Steve Sucheck - Maumee OH, US
Kenneth Marby - San Diego CA, US
Youe-kong Shue - San Diego CA, US
Yoshi Ichikawa - San Diego CA, US
David Rabuka - Oakland CA, US

C07H 17/08
A61K 31/7048
A61K 31/7052

514028000, 514029000, 536007400

This invention relates to novel macrolides, to the preparation of novel macrolides, to the use of such novel macrolides for preventing, treating, or ameliorating various conditions, and to the use of such novel macrolides as antibacterial agents.

20090209593, Aug 20, 2009

Apr 27, 2009

12/430736

Jonathan Duffield - San Diego CA, US
Alex Romero - San Diego CA, US
Yu-Hung Chiu - San Diego CA, US
David Rabuka - Oakland CA, US
Sulan Yao - San Diego CA, US
Steve Sucheck - Maumee OH, US
Kenneth Marby - San Diego CA, US
Youe-kong Shue - San Diego CA, US
Yoshi Ichikawa - San Diego CA, US

A61K 31/4439
C07D 413/14
A61K 31/424
A61P 33/02
A61P 31/04

514338, 5462717, 548218, 514375

This invention relates to novel macrolides, to the preparation of novel macrolides, to the use of such novel macrolides for preventing, treating, or ameliorating various conditions, and to the use of such novel macrolides as antibacterial agents.

20090247732, Oct 1, 2009

Nov 1, 2004

10/578603

Jonathan Duffield - San Diego CA, US
Kenneth Marby - San Diego CA, US
Sean O'Hare - Carlsbad CA, US
Yoshitaka Ichikawa - San Diego CA, US

Optimer Pharmaceuticals, Inc. - San Diego CA

C07K 9/00
C07K 1/113

530322, 530333

The present invention relates to novel glycopeptides having improved pharmacokinetic properties, improved stability, methods of preparing said novel glycopeptides, and methods to use said novel glycopeptides.

20130345410, Dec 26, 2013

Dec 20, 2012

13/722058

Optimer Pharmaceuticals, Inc. - , US
Jonathan Duffield - San Diego CA, US
Alex Romero - San Diego CA, US
Yu-Hung Chiu - Del Mar CA, US
Steve Sucheck - San Diego CA, US
Kenneth Marby - San Diego CA, US
Youe-Kong Shue - Carlsbad CA, US
Yoshiaka Ichikawa - San Diego CA, US
David Rabuka - San Diego CA, US
Sulan Yao - San Diego CA, US

OPTIMER PHARMACEUTICALS, INC. - SAN DIEGO CA

C07H 17/08
C07D 498/04

536 71, 548218, 5462717

Described herein are novel macrolides, the preparation of novel macrolides, the use of novel macrolides for preventing, treating, or ameliorating various conditions, and the use of novel macrolides as antibacterial agents.

20190062342, Feb 28, 2019

Mar 23, 2018

15/934430

- Rahway NJ, US
Jonathan Duffield - San Francisco CA, US
Alex Romero - San Diego CA, US
Yu-Hung Chiu - Del Mar CA, US
Steve Sucheck - Maumee OH, US
Kenneth Marby - San Diego CA, US
Youe-Kong Shue - Carlsbad CA, US
Yoshitaka Ichikawa - San Diego CA, US
David Rabuka - Kensington CA, US
Sulan Yao - San Diego CA, US

C07D 498/04
C07H 17/08

This invention relates to novel macrolides, to the preparation of novel macrolides, to the use of such novel macrolides preventing, treating, or ameliorating various conditions, and to the use of such novel macrolides as antibacterial agents.

20170273965, Sep 28, 2017

Aug 31, 2015

15/508550

- Rahway NJ, US
Rui Liang - East Brunswick NJ, US
Clare London - Chatham NJ, US
Kenneth Marby - San Diego CA, US
James Tata - Westfield NJ, US
Ming You - Monroe NJ, US
Yusheng Xiong - Plainsboro NJ, US

Merck Sharp & Dohme Corp. - Rahway NJ

A61K 31/47
A61K 31/16
C07C 13/04
C07D 217/06

The present invention relates to a compound represented by formula (I): and pharmaceutically acceptable salts thereof. The compounds of formula (I) are inhibitors of diacylglyceride O-acyltransferase 2 (“DGAT2”) and may be useful in the treatment, prevention and suppression of diseases mediated by DGAT2. The compounds of the present invention may be useful in the treatment of hepatic steatosis, diabetes mellitus, obesity, hyperlipidemia, hypercholesterolemia, atherosclerosis, cardiorenal diseases such as chronic kidney diseases and heart failure and related diseases and conditions.

20160280718, Sep 29, 2016

Nov 4, 2015

14/932285

- RAHWAY NJ, US
Jonathan Duffield - San Francisco CA, US
Alex Romero - San Diego CA, US
Yu-Hung Chiu - Del Mar CA, US
Steve Sucheck - Maumee OH, US
Kenneth Marby - San Diego CA, US
Youe-Kong Shue - Carlsbad CA, US
Yoshitaka Ichikawa - San Diego CA, US
David Rabuka - Kensington CA, US
Sulan Yao - San Diego CA, US

C07D 498/04
C07H 17/08

This invention relates to novel macrolides, to the preparation of novel macrolides, to the use of such novel macrolides preventing, treating, or ameliorating various conditions, and to the use of such novel macrolides as antibacterial agents.