Search

Maqbool Siddiqui Phones & Addresses

  • 7 Black Stallion Ct, Germantown, MD 20874 (301) 330-8185 (301) 916-2117
  • 7840 Epsilon Pl, Derwood, MD 20855 (301) 330-8185
  • Rockville, MD
  • 8830 Shadow Crest St, Houston, TX 77074
  • Frederick, MD
  • Gaithersburg, MD
  • Bethesda, MD
  • Violet, LA
  • Baton Rouge, LA
  • 7 Black Stallion Ct, Germantown, MD 20874 (301) 916-2117

Work

Company: National cancer institute (nci) Jun 1989 Position: Research chemist

Education

School / High School: Sir Syed University, @Engineering

Industries

Research

Resumes

Resumes

Maqbool Siddiqui Photo 1

Research Chemist

View page
Location:
Germantown, MD
Industry:
Research
Work:
National Cancer Institute (Nci)
Research Chemist

Starks Associates Buffalo Ny Jun 1984 - Jun 1987
Chemist
Maqbool Siddiqui Photo 2

Maqbool Ahmed Siddiqui

View page

Publications

Us Patents

C4′-Substituted-2-Deoxyadenosine Analogs And Methods Of Treating Hiv

View page
US Patent:
8513214, Aug 20, 2013
Filed:
Nov 10, 2008
Appl. No.:
12/741873
Inventors:
Maqbool A. Siddiqui - Silver Spring MD, US
Victor E. Marquez - Montgomery Village MD, US
Stephen H. Hughes - Smithsburg MD, US
Paul L. Boyer - Greencastle PA, US
Assignee:
The United States of America as Represented by the Secretary of the Dept. of Health and Human Services - Washington DC
International Classification:
A01N 43/04
A61K 31/70
C07H 19/16
C07H 19/167
C07H 19/173
C12Q 1/70
US Classification:
514 45, 514 46, 435 5, 536 2721, 536 276
Abstract:
The invention provides for novel 2-Deoxyadenosine compounds, which can treat HIV infection at low cytotoxicity values. Substitution at the 4′-position provided compounds which demonstrated low cytotoxicity values in an ATP-based cytotoxicity assay.

Conformationally Locked Nucleoside Analogues

View page
US Patent:
58696660, Feb 9, 1999
Filed:
Mar 14, 1997
Appl. No.:
8/818563
Inventors:
Victor E. Marquez - Gaithersbury MD
Juan B. Rodriguez - Buenos Aires, AR
Marc C. Nicklaus - Elkridge MD
Joseph J. Barchi - Bethesda MD
Maqbool A. Siddiqui - Rockville MD
Assignee:
The United States of America as represented by the Secretary of the
Department of Health and Human Services - Washington DC
International Classification:
C07D47318
C07D47334
C07D23954
C07D23947
US Classification:
544276
Abstract:
Conformationally locked 4',6'-cyclopropane-fused carboxylic nucleoside analogues. The compounds are prepared by condensing a cyclopropane-fused carbocyclic allylic alcohol with substituted purine or pyrimidine bases. The condensation products are then modified to produce the adenosine, guanosine, cytidine, thymidine, and uracil nucleoside analogues. The compounds are therapeutically useful as antimetabolites, or in the preparation of anti-metabolic agents.

Conformationally Locked Nucleoside Analogs As Antiherpetic Agents

View page
US Patent:
58407286, Nov 24, 1998
Filed:
Aug 7, 1997
Appl. No.:
8/908724
Inventors:
Victor E. Marquez - Gaithersburg MD
Marc C. Nicklaus - Elkridge MD
Joseph J. Barchi - Bethesda MD
Juan B. Rodriguez - Buenos Aires, AR
Maqbool Siddiqui - Rockville MD
Assignee:
United States of America as represented by the Department of Health and
Human services - Washington DC
International Classification:
A61K 3144
A61K 31505
A61K 3132
C07D23924
US Classification:
514261
Abstract:
A method for treatment of herpes virus infection by administering an effective virus-inhibiting amount of a cyclopropanated carbocyclic 2'-deoxynucleoside to an individual in need thereof. The nucleoside analogs are effective against herpes simplex virus types 1 and 2; Epstein-Barr Virus and human cytomegalovirus.

Conformationally Locked Nucleoside Analogues

View page
US Patent:
56294549, May 13, 1997
Filed:
Sep 23, 1994
Appl. No.:
8/311425
Inventors:
Victor E. Marquez - Gaithersburg MD
Juan B. Rodriguez - Buenos Aires, AR
Marc C. Nicklaus - Elkridge MD
Joseph J. Barchi - Bethesda MD
Maqbool A. Siddiqui - Rockville MD
Assignee:
The United States of America as represented by the Department of Health
and Human Services - Washington DC
International Classification:
C07C 49172
C07C 43196
C07C 4106
C07D47318
US Classification:
568327
Abstract:
Conformationally locked 4',6'-cyclopropane-fused carbocyclic nucleoside analogues. The compounds are prepared by condensing a cyclopropane-fused carbocyclic allylic alcohol with substituted purine or pyrimidine bases. The condensation products are then modified to produce the adenosine, guanosine, cytidine, thymidine and uracil nucleoside analogues. The compounds are therapeutically useful as antimetabolites, or in the preparation of anti-metabolic agents.

2'-Fluorofuranosyl Derivatives And Novel Method Of Preparing 2'-Fluoropyrimidine And 2'-Fluoropurine Nucleosides

View page
US Patent:
53367642, Aug 9, 1994
Filed:
Oct 29, 1992
Appl. No.:
7/968567
Inventors:
Victor E. Marquez - Bethesda MD
John S. Driscoll - Rockville MD
Ronald J. Wysocki - Potomac MD
Maqbool A. Siddiqui - Gaithersburg MD
Assignee:
The United States of America as represented by the Department of Health
and Human Services - Washington DC
International Classification:
C07G 300
US Classification:
536 41
Abstract:
A compound has the formula ##STR1## wherein R is selected from the group consisting of (C. sub. 7 -C. sub. 20)aroyl, (C. sub. 6 -C. sub. 20)aryl, aralkyl and alkylaryl, and (C. sub. 1 -C. sub. 10)alkyl-di(C. sub. 6 -C. sub. 20)aryl Si, R' is selected from the group consisting of (C. sub. 1 -C. sub. 10)alkyl, (C. sub. 7 -C. sub. 20)aroyl and (C. sub. 2 -C. sub. 12)acyl, all of which may be further substituted with O, S, N or alkyl, and R'" is selected from the group consisting of halogen, (C. sub. 1 -C. sub. 10)alkoxy, (C. sub. 1 -C. sub. 10)acyloxy, O-methane-sulfonyl and O-p-toluenesulfonyl. A composition of matter comprises 0. 001 to 99. 999 wt % of the above compound.
Maqbool A Siddiqui from Germantown, MD, age ~66 Get Report