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Michael J Frohn

from Newbury Park, CA
Age ~53
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Also known as:
Michael P Frohn, Michael I Frohn, Mike J Frohn, Michael Fruhn
Phone and address:
923 Deerspring Pl, Thousand Oaks, CA 91320
(805) 492-3484
Related to:
Michael G Critchlow, 47Brian J Critchlow, 53Michael R Henricksen, 56Brian D Frohn, 59Lori A Frohn, 44Rhonda J Frohn, 51Michael D Hill, 77Joyce E Critchlow, 96Dora R Hill, 73Shane Diffendarfer, 53Dianna J Frohn, 79
Connected to:
Ruth A Frohnapfel, 83Richard F Frohne, 70Kenneth Frohnert, 60Kenneth J Frohock, 56Sarah E Frohock, 54Robert M Frohs, 63Joleen Froias, 55Christina A Froilan, 57Joann E Froimzon, 54Frank Froio, 74

Michael Frohn Phones & Addresses

  • 923 Deerspring Pl, Newbury Park, CA 91320 (805) 492-3484
  • Thousand Oaks, CA
  • 3 Baltimore Ave, Media, PA 19063 (610) 891-7504
  • Camarillo, CA
  • Calabasas, CA
  • Philadelphia, PA
  • Huntington Beach, CA
  • Fort Collins, CO
  • Ventura, CA
  • 2808 Cedar Wood Pl, Thousand Oaks, CA 91362

Emails

r***[email protected]

Publications

Us Patents

Naphthalenone Compounds Exhibiting Prolyl Hydroxylase Inhibitory Activity, Compositions, And Uses Thereof

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US Patent:
7635715, Dec 22, 2009
Filed:
Dec 17, 2007
Appl. No.:
12/002537
Inventors:
Jennifer R. Allen - Newbury Park CA, US
Kaustav Biswas - Calabasas CA, US
Marian C. Bryan - West Hills CA, US
Roland Burli - Herts, GB
Guo-Qiang Cao - Thousand Oaks CA, US
Michael J. Frohn - Thousand Oaks CA, US
Jennifer E. Golden - Simi Valley CA, US
Stephanie Mercede - Thousand Oaks CA, US
Susana Neira - Thousand Oaks CA, US
Tanya Peterkin - Woodland Hills CA, US
Alexander J. Pickrell - Westlake Village CA, US
Anthony Reed - Oxnard CA, US
Christopher M. Tegley - Thousand Oaks CA, US
Xiang Wang - Moorpark CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
A61K 31/352
C07D 311/96
US Classification:
514451, 549331, 546 17, 546337, 544165, 5142378, 514278, 514357, 514462, 514570, 562512
Abstract:
Compounds of Formula I and Formula II are useful as inhibitors of HIF prolyl hydroxylases. Compounds of Formula I and Formula II have the following structures:.

Quinolone Based Compounds Exhibiting Prolyl Hydroxylase Inhibitory Activity

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US Patent:
7728130, Jun 1, 2010
Filed:
Dec 8, 2006
Appl. No.:
11/635683
Inventors:
Jennifer R. Allen - Newbury Park CA, US
Kaustav Biswas - Calabasas CA, US
Roland Burli - Pasadena CA, US
Jennifer Dao - Oak Park CA, US
Michael J. Frohn - Thousand Oaks CA, US
Jennifer E. Golden - Simi Valley CA, US
Randall W. Hungate - Camarillo CA, US
Robert Kurzeja - Newbury Park CA, US
Stephanie J. Mercede - Woodland Hills CA, US
Kristine M. Muller - Thousand Oaks CA, US
Susana C. Neira - Thousand Oaks CA, US
Christopher M. Tegley - Thousand Oaks CA, US
Violeta Yu - Moorpark CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
C07D 413/00
US Classification:
544128, 544105, 544238, 544333, 546152, 546157
Abstract:
This invention relates to new quinolone based compounds that exhibit prolyl hydroxylase inhibitory activity. This invention also relates to methods of increasing HIF levels or activity in a subject or treating a condition associated with HIF levels or activity in a subject by administering to the subject at least one quinolone based compound. This invention further involves assays for the detection of a hydroxyproline residue in a HIF molecule.

S1P1 Receptor Agonists And Use Thereof

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US Patent:
7842685, Nov 30, 2010
Filed:
Jun 18, 2009
Appl. No.:
12/456687
Inventors:
Victor J. Cee - Thousand Oaks CA, US
Michael J. Frohn - Thousand Oaks CA, US
Brian Alan Lanman - Oak Park CA, US
Susana C. Neira - Naperville IL, US
Anthony B. Reed - Thousand Oaks CA, US
Kelvin K. C. Sham - Thousand Oaks CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
A61K 31/397
A61K 31/4365
C07D 513/04
US Classification:
51421018, 514301, 546114
Abstract:
The present invention relates to compounds of Formula (I):.

Naphthalenone Compounds Exhibiting Prolyl Hydroxylase Inhibitory Activity, Compositions, And Uses Thereof

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US Patent:
7928139, Apr 19, 2011
Filed:
Nov 4, 2009
Appl. No.:
12/612465
Inventors:
Jennifer R. Allen - Newbury Park CA, US
Kaustav Biswas - Calabasas CA, US
Marian C. Bryan - Agoura Hills CA, US
Roland Burli - Bishop's Stortford, GB
Guo-Qiang Cao - Thousand Oaks CA, US
Michael J. Frohn - Thousand Oaks CA, US
Jennifer E. Golden - Olathe KS, US
Stephanie Mercede - Thousand Oaks CA, US
Susana Neira - Naperville IL, US
Tanya Peterkin - Gordon Town, JM
Alexander J. Pickrell - Westlake Village CA, US
Anthony Reed - Oxnard CA, US
Christopher M. Tegley - Thousand Oaks CA, US
Xiang Wang - Moorpark CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
A61K 31/352
A61K 31/195
US Classification:
514451, 514563, 514462, 514357, 514311, 514278
Abstract:
Compounds of Formula I and Formula II are useful as inhibitors of HIF prolyl hydroxylases. Compounds of Formula I and Formula II have the following structures:.

Quinolone Based Compounds Exhibiting Prolyl Hydroxylase Inhibitory Activity, And Compositions, And Uses Thereof

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US Patent:
8012968, Sep 6, 2011
Filed:
Feb 10, 2010
Appl. No.:
12/703716
Inventors:
Jennifer R. Allen - Newbury Park CA, US
Kaustav Biswas - Calabasas CA, US
Roland Burli - Pasadena CA, US
Jennifer Dao - Oak Park CA, US
Michael J. Frohn - Thousand Oaks CA, US
Jennifer E. Golden - Simi Valley CA, US
Randall W. Hungate - Camarillo CA, US
Robert Kurzeja - Newbury Park CA, US
Stephanie J. Mercede - Woodland Hills CA, US
Kristine M. Muller - Thousand Oaks CA, US
Susana C. Neira - Thousand Oaks CA, US
Christopher M. Tegley - Thousand Oaks CA, US
Violeta Yu - Moorpark CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
A61K 31/5377
A61K 31/501
A61K 31/506
A61K 31/4704
US Classification:
5142352, 51425204, 514256, 514312
Abstract:
This invention relates to new quinolone based compounds that exhibit prolyl hydroxylase inhibitory activity. This invention also relates to methods of increasing HIF levels or activity in a subject or treating a condition associated with HIF levels or activity in a subject by administering to the subject at least one quinolone based compound. This invention further involves assays for the detection of a hydroxyproline residue in a HIF molecule.

Quinolone Based Compounds Exhibiting, Prolyl Hydroxylase Inhibitory Activity, And Compositions, And Uses Thereof

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US Patent:
8017626, Sep 13, 2011
Filed:
Feb 10, 2010
Appl. No.:
12/703496
Inventors:
Jennifer R. Allen - Newbury Park CA, US
Kaustav Biswas - Calabasas CA, US
Roland Burli - Pasadena CA, US
Jennifer Dao - Oak Park CA, US
Michael J. Frohn - Thousand Oaks CA, US
Jennifer E. Golden - Simi Valley CA, US
Randall W. Hungate - Camarillo CA, US
Robert Kurzeja - Newbury Park CA, US
Stephanie J. Mercede - Woodland Hills CA, US
Kristine M. Muller - Thousand Oaks CA, US
Susana C. Neira - Thousand Oaks CA, US
Christopher M. Tegley - Thousand Oaks CA, US
Violeta Yu - Moorpark CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
A61K 31/4704
C07D 215/56
US Classification:
514312, 546155
Abstract:
This invention relates to new quinolone based compounds that exhibit prolyl hydroxylase inhibitory activity. This invention also relates to methods of increasing HIF levels or activity in a subject or treating a condition associated with HIF levels or activity in a subject by administering to the subject at least one quinolone based compound. This invention further involves assays for the detection of a hydroxyproline residue in a HIF molecule.

Heterocyclic Quinolone Derivatives That Inhibit Prolyl Hydroxylase Activity

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US Patent:
8030346, Oct 4, 2011
Filed:
Apr 29, 2008
Appl. No.:
12/150675
Inventors:
Jennifer R. Allen - Newbury Park CA, US
Roland Burli - Bishop's Shortford, GB
Michael J. Frohn - Thousand Oaks CA, US
Randall W. Hungate - Camarillo CA, US
Susana C. Neira - Thousand Oaks CA, US
Anthony B. Reed - Oxnard CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
A61K 31/385
A01N 43/42
A01N 43/78
C07D 221/22
C07D 515/02
US Classification:
514439, 514291, 514301, 514366, 514367, 514440, 546 26, 546114
Abstract:
Compounds of Formula I are useful inhibitors of HIF prolyl hydroxylases. Compounds of Formula I have the following structure:.

Pyridine And Pyrimidine Derivatives As Phosphodiesterase 10 Inhibitors

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US Patent:
8318718, Nov 27, 2012
Filed:
Nov 16, 2009
Appl. No.:
12/619573
Inventors:
Jennifer R. Allen - Newbury Park CA, US
Biswas Kaustav - Agoura Hills CA, US
Frank Chavez - Camarillo CA, US
Ning Chen - Thousand Oaks CA, US
Frenel Fils De Morin - Thousand Oaks CA, US
James R. Falsey - Moorpark CA, US
Michael J. Frohn - Thousand Oaks CA, US
Paul E. Harrington - Camarillo CA, US
Daniel B. Horne - Simi Valley CA, US
Essa Hu Harrington - Camarillo CA, US
Matthew R. Kaller - Ventura CA, US
Roxanne Kunz - Santa Monica CA, US
Holger Monenschein - Jupiter FL, US
Thomas T. Nguyen - Newbury Park CA, US
Alexander J. Pickrell - Westlake Village CA, US
Andreas Reichelt - Moorpark CA, US
Shannon Rumfelt - Camarillo CA, US
Robert M. Rzasa - Ventura CA, US
Kelvin Sham - Thousand Oaks CA, US
Guomin Yao - Camarillo CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
A61K 31/4439
A61K 31/437
A61K 31/52
A61K 31/5377
A61K 31/55
A61K 31/397
C07D 401/12
C07D 471/04
C07D 473/00
C07D 413/14
C07D 401/14
A61P 25/00
US Classification:
51421021, 514303, 514338, 51426322, 5142358, 51421208, 5462734, 546118, 544277, 544131
Abstract:
Pyridine and pyrimidine compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
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Michael J Frohn from Newbury Park, CA, age ~53 Get Report