Mitchell D Schnall

6915151, Jul 5, 2005

Feb 8, 2002

10/071434

James Baumgardner - Milmont Park PA, US
David Lipson - Wynnewood PA, US
Rahim Rizi - Montgomeryville PA, US
David Roberts - Rosemont PA, US
Mitchell Schnall - Broomall PA, US

Trustees of the University of Pennsylvania - Philadelphia PA

A61B005/055

600420, 424 93, 324307, 324309

The present invention comprises imaging and quantitative measurement of lung ventilation, particularly in a human lung. Methods for quantitative imaging of lung ventilation, and the further provided systems and algorithmic tools therefore, comprise three primary components: the combined MRI ventilation/perfusion (V/Q) imaging techniques using hyperpolarized helium-3 (He) gas (HHe); the three-dimensional quantitative imaging of absolute lung perfusion (Q) and collection of local magnetic resonance image data therefrom to produce an absolute lung perfusion image data; and the algorithmic co-registration of the two image data sets, (HP-He MRI image of V/Q and MR imaging of quantitative perfusion (Q) in the lung). From the data acquired in the combined data sets and their spatial co-registration, absolute ventilation (V) is computed.

7072706, Jul 4, 2006

Feb 8, 2002

10/071435

James Baumgardner - Milmont Park PA, US
David Lipson - Wynnewood PA, US
Rahim Rizi - Montgomeryville PA, US
David Roberts - Rosemont PA, US
Mitchell Schnall - Broomall PA, US

The Trustees of the University of Pennsylvania - Philadelphia PA

A61B 5/55

600420, 600529, 600533, 600538

The present invention offers novel equilibration methods for very high resolution, three-dimensional imaging of imaging of lung compliance and distribution of functional residual capacity (FRC) in the lung using hyperpolarized helium-3 (He) gas (HHe), and collecting local magnetic resonance image data therefrom. Using the present methods permits many functions that have been performed on a regional level for the whole lung using non-polarized helium, to be calculated for the first time from the local MRI measurements of local HHe, such as measuring volume or compliance.

8135452, Mar 13, 2012

Oct 20, 2008

12/288463

Lawrence Dougherty - Wenonah NJ, US
Hee Kwon Song - Moorestown NJ, US
Raymond Charles Boston - West Chester PA, US
Mitchell Schnall - Wayne PA, US

The Trustees Of The University Of Pennsylvania - Philadelphia PA

A61B 5/05

600420, 600407, 600408, 600410

Provided is a method for rapid, 3D, dynamic, projection reconstruction bilateral breast imaging using simultaneous multi-slab volume excitation and radial acquisition of a contrast enhanced bilateral image, in conjunction with SENSE processing, using k-Space Weighted Image Contrast (“KWIC”) filtering and multi-coil arrays for signal separation in an interleaved bilateral MR bilateral breast scan that uses conventional Cartesian sampling without parallel imaging. Software was developed for the reconstruction, modeling contrast kinetics using a heuristic model, display by parametric mapping and viewer/analysis of the multidimensional, high frame-rate bilateral breast images.

20070083615, Apr 12, 2007

Jun 4, 2004

10/558989

Robert Hollebeek - BERWYN PA, PA
Mitchell Schnall - Wayne PA, US
Barbara Beckerman - Knoxville TN, US
Patricia Payne - Knoxville TN, US
Frank Hammitt - Knoxville TN, US

G06F 15/16

709218000

A WallPlug (interface) connects DICOM devices located at a hospital to external storage and retrieval systems. The external storage and retrieval systems can be part of the National Digital Mammography Archive. The WallPlug allows secure communications within the hospital setting, and allows only selected data to be transferred between the hospital devices and the archive. The WallPlug enables cross-enterprise distribution of medical content with proper authentication and logging of transfers. The WallPlug includes two portals connected together by a private secure network. The use of two separate devices greatly enhances the security, redundancy, and manageability of the combined device.

20090313368, Dec 17, 2009

Jul 23, 2009

12/508182

Robert J. Hollebeek - Berwyn PA, US
Mitchell D. Schnall - Wayne PA, US
Barbara G. Beckerman - Knoxville TN, US
Patricia W. Payne - Knoxville TN, US
Frank Paul Hammitt - Knoxville TN, US

The Trustees of the University of Pennsylvania - Philadelphia PA

G06F 15/16
G06F 15/173
G06F 21/00

709223, 709249, 726 15

A WallPlug (interface) connects DICOM devices located at a hospital to external storage and retrieval systems. The external storage and retrieval systems can be part of the National Digital Mammography Archive. The WallPlug allows secure communications within the hospital setting, and allows only selected data to be transferred between the hospital devices and the archive. The WallPlug enables cross-enterprise distribution of medical content with proper authentication and logging of transfers. The WallPlug includes two portals connected together by a private secure network. The use of two separate devices greatly enhances the security, redundancy, and manageability of the combined device.

54760950, Dec 19, 1995

Mar 1, 1994

8/203245

Mitchell D. Schnall - Lansdowne PA
Robert E. Lenkinski - Drexel Hill PA
Herbert Y. Kressel - Wynnewood PA
Howard M. Pollack - Cheltenham PA

Medrad, Inc. - Pittsburgh PA
University of Pennsylvania - Pittsburgh PA

A61B 5055

1286532

An insertable pickup probe and interface network for magnetic resonance imaging and spectroscopy. The pickup probe in the preferred embodiment is for use in imaging the male prostate and comprises an elongated shaft supporting a patient interface balloon at its distal end which contains a RF receiving coil. The interface balloon comprises an inflatable inner balloon enclosed by a flexible outer balloon. The receiving coil is positioned between the inner and outer balloons and placed intimately adjacent the region of interest by inflating the inner balloon to expand outwardly against the outer balloon. In addition, a non-stretchable planar material is provided on the surface on the inner balloon adjacent the receiving coil for ensuring that the receiving coil is placed adjacent the region of interest. The inner balloon is inflated by an inflator cuff connected to the shaft and communicated to the inner balloon by a first lumen in the shaft. The receiving coil is electrically connected to an interconnecting cable which is connected to the proximal end of the shaft and communicated to the receiving coil by a second lumen in the shaft.

53078144, May 3, 1994

Sep 17, 1991

7/760463

Herbert Y. Kressel - Wynnesal PA
Edward J. Rhinehart - Monroeville PA
Mitchell Schnall - Lansdowne PA
Robert E. Lenkinski - Drexel Hill PA
Yutaka Imai - Tokyo, JP

Medrad, Inc. - Pittsburgh PA
The Trustees of the University of Pennsylvania - Philadelphia PA

A61B 5055
A61M 2510

1286535

An insertable intracavity probe for use in magnetic resonance imaging of an area of interest in a body cavity particularly the colon, has an elongate shaft with a handle at its proximal end and an inflatable balloon structure at its distal end. The balloon structure has an outer balloon containing a loop-type pickup coil for connection to an interfacing network. The coil is sandwiched between two internal separately inflatable balloons, and when the probe is inserted, the coil can be optimally positioned relative to the area of interest by controlled differential inflation of the balloons. The probe also has an insertable rod-like mandrel for providing twisting orbital-type movement of the balloon structure on the shaft, by rotation of the mandrel, useful to steer the probe along curves or bends in the body cavity when it is being inserted. In a modified form of the probe, the mandrel can be used to rotate the coil and the internal balloons as a unit within the outer balloon for optimal in situ angular positioning of the coil.

53480104, Sep 20, 1994

Sep 24, 1992

7/949918

Mitchell D. Schnall - Lansdowne PA
Robert E. Lenkinski - Drexel Hill PA
Herbert Y. Kressel - Wynnewood PA
Howard M. Pollack - Cheltenham PA
Theodore C. Claiborne - Gibsonia. all of PA
George J. Misic - Novelty OH
Thomas R. Welch - Gibsonia PA
Edward J. Rhinehart - Monroeville PA

Trustees of the University of Pennsylvania, Not-For-Profit Pennsylvania
Corp. - PA

A61B 555

1286532

An insertable pickup probe and interface network for magnetic resonance imaging and spectroscopy. The pickup probe in the preferred embodiment is for use in imaging the male prostate and comprises an elongated shaft supporting a patient interface balloon at its distal end which contains a RF receiving coil. The interface balloon comprises an inflatabe inner balloon enclosed by a flexible outer balloon. The receiving coil is positioned between the inner and outer balloons and placed intimately adjacent the region of interest by inflating the inner balloon to expand outwardly against the outer balloon. In addition, a non-stretchable planar material is provided on the surface on the inner balloon adjacent the receiving coil for ensuring that the receiving coil is placed adjacent the region of interest. The inner balloon is inflated by an inflator cuff connected to the shaft and communicated to the inner balloon by a first lumen in the shaft. The receiving coil is electrically connected to an interconnecting cable which is connected to the proximal end of the shaft and communicated to the receiving coil by a second lumen in the shaft.