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Natalia Sedkova

from Medford, MA
Age ~61
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Also known as:
Natalia Sedkov, Iourii Sedkov
Related to:
Alexander SedkovYuri SedkovYurii Sedkov, 64
Connected to:
Amr M Sedky, 73Alan K Sedlacek, 60Albert J Sedlacek, 91Heather Sedlacek, 49Janet N Sedlacek, 56Scot M Sedlacek, 69Kate R Sedlack, 40Lynn C Sedlack, 61Betsy Sedlak, 44Cecilia J Sedlak, 84

Natalia Sedkova Phones & Addresses

  • Medford, MA
  • White Plains, NY
  • Cherry Hill, NJ
  • Wilmington, DE
  • Lindenwold, NJ
  • Memphis, TN

Publications

Us Patents

Genes Encoding Carotenoid Compounds

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US Patent:
7070952, Jul 4, 2006
Filed:
Mar 19, 2004
Appl. No.:
10/804677
Inventors:
Qiong Cheng - Wilmington DE, US
Natalia Sedkova - Cherry Hill NJ, US
Luan Tao - Claymont DE, US
Assignee:
E. I. du Pont Nemours and Company - Wilmington DE
International Classification:
C12P 5/00
C12P 5/02
C12N 9/00
C12N 1/20
C12N 1/14
US Classification:
435 67, 4352523, 435183, 435325, 43525411, 4352572, 435419, 43525421, 43525422, 43525423, 4352546, 4352522, 43525231, 43525232, 43525233, 43525234, 43525235, 536 232
Abstract:
Genes have been isolated from encoding geranylgeranyl pyrophosphate (GGPP) synthase (CrtE), phytoene synthase (CrtB), phytoene desaturase (Crtl), lycopene cyclase (CrtY), β-carotene hydroxylase (CrtZ), and zeaxanthin glucosyl transferase (CrtX) activity. The genes and their products are useful for the conversion of farnesyl pyrophosphate to carotenoids. Vectors containing those DNA segments, host cells containing the vectors and methods for producing those enzymes by recombinant DNA technology in transformed host organisms are disclosed.

Carotenoid Hydroxylase Enzymes

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US Patent:
7091031, Aug 15, 2006
Filed:
Aug 9, 2005
Appl. No.:
11/200394
Inventors:
Qiong Cheng - Wilmington DE, US
Luan Tao - Havertown PA, US
Natalia Sedkova - Cherry Hill NJ, US
Assignee:
E. I. du Pont de Nemours and Company - Wilmington DE
International Classification:
C12N 1/21
C12N 1/13
C12N 1/15
C12N 1/19
C12N 5/10
C12N 15/63
C12N 9/02
US Classification:
4352523, 435189, 4353201, 4352541, 4352551, 435419, 435411, 435412, 435414, 435415, 4352521, 43525231, 43525232, 43525233, 43525234, 43525235, 43525421, 43525422, 43525423, 4352543, 4352546, 4352572, 536 232
Abstract:
A novel CrtZ carotenoid hydroxylase, isolated from DC263, is provided that is useful for the production of hydroxylated carotenoids. Additionally, a previously identified hypothetical protein from has found to have carotenoid hydroxylase activity. Both hydroxylase genes exhibit low homology in comparison to other CrtZ hydroxylases previously reported. Expression of the hydroxylases in heterologous host cells enabled production of hydroxylated carotenoids.

Optimized Bacterial Host Strains Of 16A

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US Patent:
7232666, Jun 19, 2007
Filed:
Nov 24, 2004
Appl. No.:
10/997844
Inventors:
Pamela L. Sharpe - Newark DE, US
Qiong Cheng - Wilmington DE, US
Melissa D. Bosak - Deptford NJ, US
Luan Tao - Claymont DE, US
Natalia Sedkova - Cherry Hill NJ, US
Assignee:
E. I. du Pont de Nemours and Company - Wilmington DE
International Classification:
C12P 23/00
C07H 21/04
C12N 9/10
C12N 15/74
C12N 1/21
US Classification:
435 67, 435193, 4352523, 435471, 435 691, 536 232
Abstract:
Methanotrophic bacterial strains are provided that have been optimized for the production of carotenoid compounds through the down-regulation of one or more of the crtN1, ald, crtN2 and crtN3 genes of the carotenoid biosynthetic pathway. The resulting strains lack pigmented Ccarotenoid compounds, and show an increase in the production of Ccarotenoids. The use of the optimized host strains for the production of the Ccarotenoids canthaxanthin and astaxanthin is also described.

Genes Of Strain Dc413 Encoding Enzymes Involved In Biosynthesis Of Carotenoid Compounds

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US Patent:
7288387, Oct 30, 2007
Filed:
Mar 26, 2004
Appl. No.:
10/810733
Inventors:
Qiong Cheng - Wilmington DE, US
Luan Tao - Claymont DE, US
Natalia Sedkova - Wilmington DE, US
Assignee:
E. I. du Pont de Nemours and Company - Wilmington DE
International Classification:
C07H 21/02
C12P 23/00
C12N 15/00
C12N 1/12
US Classification:
435 67, 4353201, 4352523, 43525411, 4352542, 4352571, 536 231
Abstract:
A carotenogenic biosynthetic gene cluster has been isolated from strain DC413, wherein the genetic organization of the cluster is crtE-idi-crtX-crtY-crtI-crtB-crtZ. The genes contained within this cluster encode geranylgeranyl pyrophosphate (GGPP) synthetase (CrtE), isopentenyl pyrophosphate isomerase (Idi), zeaxanthin glucosyl transferase (CrtX), lycopene cyclase (CrtY), phytoene desaturase (CrtI), phytoene synthase (CrtB), and β-carotene hydroxylase (CrtZ). The gene cluster, genes and their products are useful for the conversion of farnesyl pyrophosphate to carotenoids. Vectors containing those DNA segments, host cells containing the vectors and methods for producing those enzymes by recombinant DNA technology in transformed host organisms are disclosed.

Solvent Tolerant Microorganisms And Methods Of Isolation

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US Patent:
7541173, Jun 2, 2009
Filed:
Jun 12, 2007
Appl. No.:
11/761497
Inventors:
Michael G. Bramucci - Boothwyn PA, US
Vasantha Nagarajan - Wilmington DE, US
Natalia Sedkova - Cherry Hill NJ, US
Manjari Singh - West Chester PA, US
Assignee:
E.I. du Pont de Nemours and Company - Wilmington DE
International Classification:
C12N 1/20
C12N 1/21
C12P 7/16
US Classification:
4352523, 435148, 435160, 4352522, 43525231, 43525234, 4352524, 4352529
Abstract:
p-00010000.

Solvent Tolerant Microorganisms And Methods Of Isolation

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US Patent:
7659104, Feb 9, 2010
Filed:
May 2, 2007
Appl. No.:
11/743220
Inventors:
Michael G. Bramucci - Boothwyn PA, US
Vasantha Nagarajan - Wilmington DE, US
Natalia Sedkova - Cherry Hill NJ, US
Manjari Singh - West Chester PA, US
Assignee:
E.I. du Pont de Nemours and Company - Wilmington DE
International Classification:
C12N 1/20
C12P 7/16
C12N 1/21
C12N 1/00
C12N 1/32
US Classification:
4352521, 435160, 435243, 435247, 4352523
Abstract:
p-00010000.

Method For The Production Of 1-Butanol

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US Patent:
8426173, Apr 23, 2013
Filed:
Apr 28, 2008
Appl. No.:
12/110503
Inventors:
Michael G. Bramucci - Boothwyn PA, US
Dennis Flint - Newark DE, US
Vasantha Nagarajan - Wilmington DE, US
Natalia Sedkova - Cherry Hill NJ, US
Manjari Singh - West Chester PA, US
Tina K. Van Dyk - Wilmington DE, US
Assignee:
Butamax (TM) Advanced Biofuels LLC - Wilmington DE
International Classification:
C12P 7/16
US Classification:
435160, 435165
Abstract:
A method for the production of 1-butanol by fermentation using a microbial production host is disclosed. The method employs a reduction in temperature during the fermentation process that results in a more robust tolerance of the production host to the butanol product.

Method For The Production Of 2-Butanol

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US Patent:
8426174, Apr 23, 2013
Filed:
Apr 28, 2008
Appl. No.:
12/110510
Inventors:
Michael G. Bramucci - Boothwyn PA, US
Dennis Flint - Newark DE, US
Vasantha Nagarajan - Wilmington DE, US
Natalia Sedkova - Cherry Hill NJ, US
Manjari Singh - West Chester PA, US
Tina K. Van Dyk - Wilmington DE, US
Assignee:
Butamax(TM) Advanced Biofuels LLC - Wilmington DE
International Classification:
C12P 7/16
US Classification:
435160
Abstract:
A method for the production of 2-butanol by fermentation using a microbial production host is disclosed. The method employs a reduction in temperature during the fermentation process that results in a more robust tolerance of the production host to the butanol product.
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Natalia Sedkova from Medford, MA, age ~61 Get Report