US Patent:
20040162298, Aug 19, 2004
Inventors:
Richard Dalterio - Chester CT, US
Qi Guo - Newtown PA, US
International Classification:
A61K031/522
Abstract:
A method of inhibiting HIV infection in a mammal by administering to said mammal in need thereof a small molecule compound having a molecular weight of less than about 1,000 dalton, wherein said compound interacts with HIV-gp120 in such a manner as to cause conformational change in said gp120 thereby preventing interaction between said gp120 and leukocyte CD4.