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Robert Dedinas Phones & Addresses

  • 109 Smith Woods Ln, Newark, DE 19711 (302) 731-1499 (302) 731-5201
  • 276 Belfield Rd, Newark, DE 19713 (302) 731-1499 (302) 731-5201
  • Wilmington, DE
  • 109 Smith Woods Ln, Newark, DE 19711 (302) 463-3552

Work

Position: Handlers, Equipment Cleaners, Helpers, and Laborers Occupations

Education

Degree: Graduate or professional degree

Publications

Us Patents

Naphthalenecarboxamides As Tachykinin Receptor Antagonists

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US Patent:
6500818, Dec 31, 2002
Filed:
Mar 30, 2001
Appl. No.:
09/806620
Inventors:
Peter Robert Bernstein - Wilmington DE
Robert Frank Dedinas - Wilmington DE
Cyrus John Ohnmacht - Wilmington DE
Keith Russell - Wilmington DE
Assignee:
Astrazeneca AB - Sodertalje
International Classification:
C07D40104
US Classification:
51421101, 546187, 546188, 546205, 546206, 546197, 544 3, 544 8, 544332, 540492, 540524, 540544, 540545, 51421108, 51421208, 514218, 514316, 514319, 514321, 5142225, 5142222, 514274
Abstract:
Compounds having the following formula wherein L, M, R , R , R , R , R , R , X and X are as defined in the specification, pharmaceutically-acceptable salt thereof, useful for treating depression, anxiety, asthma, rheumatoid arthritis, Alzheimers disease, cancer, schizophrenia, oedema, allergic rhinitis, inflammation, pain, gastrointestinal-hypermotility, emesis, Huntingtons disease, psychoses, hypertension, migraine, bladder hypermotility, or urticaria, compositions including such compounds and processes for making such compounds.

Naphthamide Derivatives And Their Use

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US Patent:
20060241142, Oct 26, 2006
Filed:
Aug 26, 2003
Appl. No.:
10/525303
Inventors:
Peter Bernstein - Wallingford PA, US
Cathy Dantzman - Wilmington DE, US
Robert Dedinas - Newark DE, US
Lihong Shen - Wilmington DE, US
Paul Warwick - Wilmington DE, US
International Classification:
C07D 211/06
A61K 31/445
US Classification:
514319000, 546205000
Abstract:
Compounds having the following structure wherein R, R, R, R, m and n are as defined in the specification, in vivo-hydrolysable precursors thereof, pharmaceutically-acceptable salts thereof, the use in therapy and pharmaceutical compositions and methods of treatment using the same.

N-Substituted Naphthalene Carboxamides As Neurokinin-Receptor Antagonists

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US Patent:
6365602, Apr 2, 2002
Filed:
Jan 5, 2001
Appl. No.:
09/743335
Inventors:
Peter Bernstein - Wallingford PA
Robert Dedinas - Newark DE
Keith Russell - Newark DE
Assignee:
Astra Zeneca AB
International Classification:
A61K 31445
US Classification:
514319, 514269, 514316, 514326, 544316, 546205, 546208, 546188
Abstract:
A compound of formula I wherein: R is alkyl; R is optionally substituted phenyl 2-oxo-tetrahydro-1(2H)-pyrimidinyl, or 2-oxo-1-piperidinyl; R is hydrogen, alkoxy, alkanoyloxy, alkoxycarbonyl, alkanoylamino, acyl, alkyl, carbamoyl, N-alkylcarbamoyl, N,N-dialkylcarbamoyl where the alkyl groups are the same or different, hydroxy, thioacyl, thiocarbamoyl, N-alkylthiocarbamoyl, or N,N-dialkylthiocarbamoyl where the alkyl groups are the same or different. X and X are independently hydrogen or halo, provided that at least one of X or X is halo; and R , R , R and R are independently hydrogen, cyano, nitro, trifluoromethoxy, trifluoromethyl, or alkylsulfonyl are antagonists of at least one tachykinin receptor and are useful in the treatment of depression, anxiety, asthma, pain, inflammation, urinary incontinence and other disease conditions. Process for their preparation are described, as are compositions containing them and their use.
Robert F Dedinas from Newark, DE, age ~80 Get Report