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Robert George Rohwer

from Ellicott City, MD
Age ~79

Robert Rohwer Phones & Addresses

  • 4128 Arjay Cir, Ellicott City, MD 21042 (410) 313-9360
  • 5145 Homecoming Ln, Columbia, MD 21044
  • Annapolis, MD
  • Pittsboro, NC
  • 4128 Arjay Cir, Ellicott City, MD 21042

Publications

Us Patents

Methods For Rapid Screening Of Mad Cow Disease And Other Transmissible Spongiform Encephalopathies

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US Patent:
20080145312, Jun 19, 2008
Filed:
Feb 15, 2008
Appl. No.:
12/032397
Inventors:
Cha Min Tang - Wayne PA, US
Robert G. Rohwer - Ellicott City MD, US
International Classification:
A61K 49/00
G01N 33/53
US Classification:
424 91, 435 792, 435 71
Abstract:
Methods for diagnosing altered neuropathology in an animal are disclosed, wherein said methods comprise imaging brain, spinal cord, or other neural tissue of the animal, analyzing the appearance of the tissue, and determining whether the appearance of the tissue is altered relative to corresponding unaltered tissue. Also disclosed are methods for diagnosing spongiform encephalopathies in an animal, wherein said methods comprise imaging brain, spinal cord, or other neural tissues of the animal, analyzing the appearance of vacuoles in the tissue, and determining whether the appearance of the vacuoles in the tissue is altered relative to corresponding spongiform encephalopathy-free tissue. Also disclosed are automated methods for diagnosing altered neuropathy and spongiform encephalopathies.

Methods For Detecting And Inactivating A Prion

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US Patent:
20090068640, Mar 12, 2009
Filed:
Nov 12, 2008
Appl. No.:
12/269479
Inventors:
Robert ROHWER - Ellicott City MD, US
Luisa Gregori - Baltimore MD, US
International Classification:
C12Q 1/70
A61L 2/00
US Classification:
435 5, 422 38
Abstract:
A method for the isolation or detection of a prion in a sample is disclosed. Also disclosed are methods for the disinfection and/or decontamination and/or inactivation of TSE infectivity.

Method For Rapid Screening Of Mad Cow Disease And Other Transmissible Spongiform Encephalopathies

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US Patent:
20090209867, Aug 20, 2009
Filed:
Apr 24, 2009
Appl. No.:
12/429330
Inventors:
Cha Min TANG - Wayne PA, US
Robert G. ROHWER - Ellicott City MD, US
International Classification:
A61B 6/00
G01N 33/53
C12Q 1/02
US Classification:
600476, 435 792, 435 29
Abstract:
Methods for diagnosing altered neuropathology in an animal are disclosed, wherein said methods comprise imaging brain, spinal cord, or other neural tissue of the animal, analyzing the appearance of the tissue, and determining whether the appearance of the tissue is altered relative to corresponding unaltered tissue. Also disclosed are methods for diagnosing spongiform encephalopathies in an animal, wherein said methods comprise imaging brain, spinal cord, or other neural tissues of the animal, analyzing the appearance of vacuoles in the tissue, and determining whether the appearance of the vacuoles in the tissue is altered relative to corresponding spongiform encephalopathy-free tissue. Also disclosed are automated methods for diagnosing altered neuropathy and spongiform encephalopathies.

Efficiency Of Prion Conversion In Vitro And Sensitivity Of Prion Detection

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US Patent:
20130115637, May 9, 2013
Filed:
Jul 8, 2011
Appl. No.:
13/808860
Inventors:
Ilia V. Baskakov - Columbia MD, US
Robert G. Rohwer - Ellicott City MD, US
Natallia Makarava - Baltimore MD, US
Assignee:
The United States of America as represented by the Dept. of Veterans Office of General Counsel - Washington DC
UNIVERSITY OF MARYLAND, BALTIMORE - Baltimore MD
International Classification:
G01N 33/68
US Classification:
435 792, 436501, 4352872, 422430
Abstract:
The present invention relates to improved methods and kits for the amplification detection of pathogenic prion proteins in samples. In some aspects of the invention, the method comprises: i) contacting the sample with a source of PrPto make a reaction mixture; ii) incubating the reaction mixture; iii) agitating the reaction mixture of (ii) in the presence of one or more beads; and iv) detecting the amplified PrP. The present invention also provides methods of screening to identify agents that modulate PrPformation, by carrying out the methods of the invention in the presence and absence of the agent, and comparing the amount of PrPgenerated between the samples. The present methods can be employed to obtain quantities of PrPfor structural or other studies.

Methods For Detecting And Inactivating A Prion

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US Patent:
20060228696, Oct 12, 2006
Filed:
Jun 27, 2003
Appl. No.:
10/520785
Inventors:
Robert Rohwer - Ellicott City MD, US
Luisa Gregori - Baltimore MD, US
International Classification:
C12Q 1/70
A61L 2/00
US Classification:
435005000, 422038000
Abstract:
A method for the isolation or detection of a prion in a sample is disclosed. Also disclosed are methods for the disinfection and/or decontamination and/or inactivation of TSE infectivity.
Robert George Rohwer from Ellicott City, MD, age ~79 Get Report