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Steven M Birken

from Damascus, MD
Age ~78
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Also known as:
Steve M Birken, Steven R
Phone and address:
24701 Tandem Dr, Damascus, MD 20872
(301) 253-4222
Related to:
Tze ChanAnnette Campo, 65Eric Tricolla, 66Maria Collura, 70Marc Luvshis, 67George Luvshis
Connected to:
Scott L Birken, 47Adam B Birkenhead, 52Jessica Birkenhauer, 37Robert A Birkenheier, 63Robert W Birkenhead, 51David M Birkenmeier, 50Nancy K Birkenstock, 61Richard P Birkenwald, 71James D Birkes, 61John E Birkes, 97

Steven Birken Phones & Addresses

  • 24701 Tandem Dr, Damascus, MD 20872 (301) 253-4222
  • Hastings on Hudson, NY
  • Gaithersburg, MD
  • 7812 Briardale Rd, Derwood, MD 20855 (301) 963-2206
  • 120 Oneida Ave, Dumont, NJ 07628 (201) 384-7059
  • New York, NY
  • Hackettstown, NJ
  • Oceanside, NY
  • 24701 Tandem Dr, Damascus, MD 20872 (201) 384-7059

Work

Company: Nih office of the director Position: Program officer

Education

Degree: Associate degree or higher

Resumes

Resumes

Steven Birken Photo 1

Program Officer

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Location:
Damascus, MD
Work:
Nih Office of the Director
Program Officer

Publications

Us Patents

Methods Of Using Antibodies Against Hormone-Related Determinants

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US Patent:
6339143, Jan 15, 2002
Filed:
Jun 7, 1995
Appl. No.:
08/487949
Inventors:
Alexander Krichevsky - Fox Chapel PA
Steven Birken - Dumont NJ
John OConnor - New Rochelle NY
Robert E. Canfield - Cold Spring NY
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
K07K 6126
US Classification:
53038824, 5303881, 435325, 435326, 435336
Abstract:
This invention provides methods for detecting the presence of human malignant cells in a sample of tumor cells; determining whether a tumor present in a human subject is malignant; obtaining an enriched population of live human malignant cells; determining the amount of intact luteinizing hormone in a sample; determining the ovulatory stage of a subject; determining the amount of intact follicle stimulating hormone in a sample; determining the ovulatory stage of a subject; determining the amount of intact human chorionic gonadotropin in a sample; determining whether a subject is pregnant; determining the ovulatory stage of a subject; determining the amount of free subunit of human luteinizing hormone in a sample; determining whether a subject has a malignant tumor; determining the amount of nicked human chorionic gonadotropin in a sample; and determining the likelihood of a fetuss being afflicted with Downs syndrome.

Methods For Predicting Pregnancy Outcome In A Subject By Hcg Assay

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US Patent:
6500627, Dec 31, 2002
Filed:
Feb 3, 1998
Appl. No.:
09/017976
Inventors:
John F. OConnor - New Rochelle NY
Galina I. Kovalevskaya - New York NY
Steven Birken - Dumont NJ
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
G01N 33543
US Classification:
435 792, 435 71, 435 75, 435 79, 435 794, 436501, 436814, 436818, 5303875, 53038824, 5303892
Abstract:
The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG is a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.

Determination Of The Amount Of Hlh Core Fragment In A Sample From A Subject And Uses Thereof

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US Patent:
6521416, Feb 18, 2003
Filed:
Aug 1, 2000
Appl. No.:
09/630273
Inventors:
Steven Birken - Dumont NJ
Yacov Maydelman - Fort Lee NJ
Galina I. Kovalevskaya - New York NY
John F. OConnor - New Rochelle NY
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
C12Q 158
US Classification:
435 12, 435 71, 435 792, 435 4
Abstract:
The present invention provides a method for predicting the likely timing of the onset of menopause for a perimenopausal female subject by determining the amount of hLHcf in a sample from the subject comprising the steps of: (a) contacting a sample from the subject with an antibody which specifically binds to hLHcf without substantially cross-reacting with hLH, hLH or hLHcf, under conditions permitting formation of a complex between the antibody and hLHcf; (b) measuring the amount of complex formed, so as to thereby determine the amount of hLHcf in the sample; and (c) comprising the amount of hLHcf in the subjects sample determined in step (b) with either (i) the amount determined for known postmenopausal female subject or (ii) the amount determined for a sample from a known premenopausal female subject, wherein an amount of hLHcf in the sample similar to the amount of hLHcf in the known postmenopausal sample indicates temporal proximity to the onset of menopause, and an amount of hLHcf in the sample similar to the amount of hLHcf in the known premenopausal sample indicates temporal distance from the onset of menopause for the subject. AS described herein amount is both concentration and pattern of measurement of concentrations in one or more consecutive urine specimens.

Methods For Detecting Trophoblast Malignancy By Hcg Assay

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US Patent:
6927034, Aug 9, 2005
Filed:
May 13, 1999
Appl. No.:
09/311428
Inventors:
John O'Connor - New Rochelle NY, US
Steven Birken - Dumont NJ, US
Galina Kovalevskaya - Bronx NY, US
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
G01N033/543
G01N033/537
US Classification:
435 792, 435 71, 435 75, 435 79, 435 794, 436501, 436814, 436818, 5303875, 53038824, 5303892
Abstract:
The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.

Antibodies Specific For Hlh Βcore Fragment And Uses Thereof

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US Patent:
7034124, Apr 25, 2006
Filed:
Sep 23, 1999
Appl. No.:
09/404076
Inventors:
Robert E. Canfield - Cold Spring NY, US
Steven Birken - Dumont NJ, US
John O'Connor - New Rochelle NY, US
Galina Kovalevskaya - New York NY, US
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
C07K 16/00
US Classification:
5303892, 53038824
Abstract:
This invention provides an antibody which specifically binds to hLHβcf without cross-reacting with hLH, hLHβ or hCGβcf. In an embodiment, the monoclonal antibody is designated B505. In a further embodiment, the hybridoma cell line producing the monoclonal antibody B 505 is designated ATCC Accession No. 12000. This invention provides different uses of the antibodies. Finally, this invention provides a method for determining the amount of hLHβcf or hLHβcf-related molecule in a sample.

Methods For Predicting Pregnancy Outcome In A Subject By Hcg Assay

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US Patent:
7198954, Apr 3, 2007
Filed:
Aug 1, 2000
Appl. No.:
09/630215
Inventors:
John F. O'Connor - New Rochelle NY, US
Galina I. Kovalevskaya - New York NY, US
Steven Birken - Dumont NJ, US
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
G01N 33/48
G01N 33/53
C07K 16/00
US Classification:
436 65, 435 71, 435 75, 435 792, 435 794, 436501, 436518, 436524, 436528, 436811, 436547, 436548, 5303875, 53038824, 5303892
Abstract:
The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.

Diagnostic Kit For Predicting The Onset Of Menopause

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US Patent:
7229781, Jun 12, 2007
Filed:
May 31, 2002
Appl. No.:
10/159354
Inventors:
Steven Birken - Dumont NJ, US
Yacov Maydelman - Fort Lee NJ, US
Galina I. Kovalevskaya - New York NY, US
John F. O'Connor - New Rochelle NY, US
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
G01N 33/50
G01N 33/53
G01N 33/536
G01N 33/537
G01N 33/541
US Classification:
435 792, 435 71, 435 75, 5303871
Abstract:
The present invention provides methods to quantitate the hLHβ core fragment in a sample. The present invention now makes it possible to evaluate the metabolism of hLH in premenopausal, perimenopausal and postmenopausal women and to distinguish between normal and abnormal physiological states.

Methods For Predicting Pregnancy Outcome In A Subject By Hcg Assay

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US Patent:
7285391, Oct 23, 2007
Filed:
Sep 1, 2004
Appl. No.:
10/931956
Inventors:
John O'Connor - New Rochelle NY, US
Steven Birken - Dumont NJ, US
Galina Kovalevskaya - Bronx NY, US
Assignee:
The Trustees of Columbia Univeristy in the City of New York - New York NY
International Classification:
G01N 33/00
G01N 33/53
A61K 39/395
US Classification:
435 71, 435 75, 435 79, 435 792, 435 794, 436501, 436814, 436818, 5303875, 53038824, 5303892, 4241301
Abstract:
The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.
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Steven M Birken from Damascus, MD, age ~78 Get Report