Inventors:
HANS BOEHRINGER - San Diego CA, US
Mark Daquipa - San Diego CA, US
Hsin Ming Yang - San Diego CA, US
Thomas L. Pisani - Winchester MA, US
Sumitra Nag - Lexington MA, US
Jay Salhaney - Holliston MA, US
Marcella B. Holdridge - Watertown MA, US
Erika Johnston - Lexington MA, US
Jeremy Schonhorn - Hopkinton MA, US
International Classification:
G01N 21/78
Abstract:
Disclosed herein are indirect lateral flow sandwich assays, in which the target analyte binds an analyte-specific reagent comprising a first member of a conjugate pair, forming a complex which contacts and binds a colored particulate label comprising a complementary member of said conjugate pair, forming a second complex. Capture of this analyte-comprising, second complex by an immobilized analyte specific capture reagent results in the formation of an immobilized labeled sandwich complex that can be detected.