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Torsten Herbertz

from Stow, MA
Age ~59

Torsten Herbertz Phones & Addresses

  • 25 Woodland Way, Stow, MA 01775 (978) 310-7413
  • 217 4Th St, Highland Park, NJ 08904 (732) 572-8931
  • 16 Oak St, New Brunswick, NJ 08901 (908) 745-0354
  • 210 Byers Rd, Chester Springs, PA 19425 (610) 458-7253
  • 90 Hillbrook Dr, Honey Brook, PA 19344 (610) 273-2793 (732) 572-8931
  • Emerson, NJ
  • Chester, PA

Publications

Us Patents

Compounds, Compositions And Methods For Treating Or Preventing Pneumovirus Infection And Associated Diseases

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US Patent:
20050288345, Dec 29, 2005
Filed:
Aug 11, 2003
Appl. No.:
10/524313
Inventors:
David Rys - Philadelphia PA, US
Theodore Nitz - Pottstown PA, US
Janet Gaboury - Blue Bell PA, US
Christopher Burns - Malvern PA, US
Daniel Pevear - Harleysville PA, US
Thomas Lessen - Langhorne PA, US
Torsten Herbertz - Honey Brook PA, US
International Classification:
A61K031/41
C07D043/02
US Classification:
514381000, 548252000
Abstract:
Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the subfamily of and diseases associated with such infections.

Pyranouidole Derivatives And The Use Thereof For The Treatment Of Hepatitis C Virus Infection Or Disease

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US Patent:
20070219212, Sep 20, 2007
Filed:
Mar 1, 2005
Appl. No.:
10/589453
Inventors:
Stephen Condon - Glenmoore PA, US
Randy Jackson - Glenmoore PA, US
Matthew Laporte - Honey Brook PA, US
Christopher Burns - Malvern PA, US
Torsten Herbertz - Honey Brook PA, US
Janet Gaboury - Blue Bell PA, US
International Classification:
A61K 31/407
C07D 491/02
US Classification:
514252060, 514411000, 546276700, 548364400, 548427000, 549396000
Abstract:
The invention is directed to novel pyranoindole derivatives and analogs as well as compositions containing the same and to the use thereof for the treatment, prevention or inhibition of viral infections and associated diseases caused by the Hepatitis C virus.

Compounds, Compositions And Methods For Treating Or Preventing Pneumovirus Infection And Associated Diseases

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US Patent:
20110305666, Dec 15, 2011
Filed:
Aug 23, 2011
Appl. No.:
13/216106
Inventors:
David J. Rys - Philadelphia PA, US
Theodore J. Nitz - Pottstown PA, US
Janet A. Gaboury - Blue Bell PA, US
Christopher J. Burns - Malvern PA, US
Daniel C. Pevear - Harleysville PA, US
Thomas A. Lessen - Langhorne PA, US
Torsten Herbertz - Honey Brook PA, US
International Classification:
A61K 31/41
A61P 37/02
A61K 39/395
A61P 31/14
A61K 38/21
A61K 31/7056
US Classification:
424 854, 514381, 514 43, 4241301
Abstract:
Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infections.

Inhibiting Cyclic Amp-Responsive Element-Binding Protein (Creb)

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US Patent:
20220213089, Jul 7, 2022
Filed:
Mar 13, 2020
Appl. No.:
17/439646
Inventors:
- Watertown MA, US
Torsten HERBERTZ - Watertown MA, US
Hongbin LI - Madison CT, US
Bradford GRAVES - Watertown MA, US
Steven MISCHKE - Waltham MA, US
Angela V. WEST - Watertown MA, US
Anna ERICSSON - Shrewsbury MA, US
Jennifer R. DOWNING - Watertown MA, US
International Classification:
C07D 471/04
Abstract:
The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains (e.g., certain forms of cancer), and methods of synthesis of these compounds.

Tetrahydroquinoline Compositions As Bet Bromodomain Inhibitors

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US Patent:
20230061891, Mar 2, 2023
Filed:
Jul 23, 2021
Appl. No.:
17/383610
Inventors:
- Watertown MA, US
Torsten Herbertz - Stow MA, US
Goss S. Kauffman - Ledyard CT, US
Katherine J. Kayser-Bricker - Branford CT, US
George P. Luke - Clinton CT, US
Matthew W. Martin - Arlington MA, US
David S. Millan - Watertown MA, US
Shawn E.R. Schiller - Haverhill MA, US
Adam C. Talbot - Watertown MA, US
International Classification:
C07D 401/04
C07D 401/14
A61K 31/4709
A61K 45/06
A61K 31/47
A61K 31/497
A61K 31/506
A61K 31/5377
C07D 405/14
C07D 413/14
C07D 215/20
C07D 215/48
C07D 409/14
C07D 413/04
C07D 417/04
C07D 417/14
C07D 471/04
C07D 473/28
C07D 487/04
A61K 31/517
A61K 31/519
A61K 31/496
A61K 31/501
A61K 31/52
C07D 401/12
C07D 405/04
C07D 417/10
Abstract:
The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula I:wherein W, X, Y, Z, R, R, R, and Rare as described herein.

Tetrahydroquinoline Compositions As Bet Bromodomain Inhibitors

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US Patent:
20200369642, Nov 26, 2020
Filed:
Jan 28, 2020
Appl. No.:
16/774515
Inventors:
- Watertown MA, US
Torsten Herbertz - Stow MA, US
Goss S. Kauffman - Ledyard CT, US
Katherine J. Kayser-Bricker - Branford CT, US
George P. Luke - Clinton CT, US
Matthew W. Martin - Arlington MA, US
David S. Millan - Watertown MA, US
Shawn E.R. Schiller - Haverhill MA, US
Adam C. Talbot - Watertown MA, US
International Classification:
C07D 401/04
C07D 401/14
A61K 31/4709
A61K 45/06
A61K 31/47
A61K 31/497
A61K 31/506
A61K 31/5377
C07D 405/14
C07D 413/14
C07D 215/20
C07D 215/48
C07D 409/14
C07D 413/04
C07D 417/04
C07D 417/14
C07D 471/04
C07D 473/28
C07D 487/04
A61K 31/517
A61K 31/519
A61K 31/496
A61K 31/501
A61K 31/52
C07D 401/12
C07D 405/04
C07D 417/10
Abstract:
The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula I:wherein W, X, Y, Z, R, R, R, and Rare as described herein.

Inhibiting Creb Binding Protein (Cbp)

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US Patent:
20200299295, Sep 24, 2020
Filed:
Jun 8, 2020
Appl. No.:
16/946159
Inventors:
- Watertown MA, US
Torsten Herbertz - Stow MA, US
Hongbin Li - Madison CT, US
Bradford Graves - Nutley NJ, US
Steven Mischke - Waltham MA, US
Angela West - Franklin MA, US
Jennifer R. Downing - Clinton MA, US
Anna Ericsson - Shrewsbury MA, US
International Classification:
C07D 471/04
Abstract:
The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains, and methods of synthesis of these compounds.

Tetrahydro-Imidazo Quinoline Compositions As Cbp/P300 Inhibitors

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US Patent:
20200216445, Jul 9, 2020
Filed:
Sep 14, 2018
Appl. No.:
16/647478
Inventors:
- Watertown MA, US
Torsten Herbertz - Stow MA, US
Hongbin Li - Madison CT, US
Bradford Graves - Nutley NJ, US
Steven Mischke - Waltham MA, US
Angela V. West - Franklin MA, US
Jennifer R. Downing - Clinton MA, US
Anna Ericsson - Shrewsbury MA, US
International Classification:
C07D 471/04
C07D 519/00
A61P 35/00
Abstract:
The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains, and methods of synthesis of these compounds.
Torsten Herbertz from Stow, MA, age ~59 Get Report