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Wolfgang K Goetzinger

from Boston, MA
Deceased
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Connected to:
Dale A Goetzke, 53Jaclyn E Goetzke, 35Heidi J Goetzman, 48Jordan O Goetzman, 46Ryan R Goewert, 31Judy A Goewey, 78Julie GoeweyPaul M Gofberg, 55Carleton N Goff, 109Carlos R Goff, 69

Wolfgang Goetzinger Phones & Addresses

  • Boston, MA
  • Waltham, MA
  • 350 W 2Nd St UNIT 7, Boston, MA 02127 (617) 283-3655

Work

Company: Amgen Dec 31, 2006 Position: Director, research

Education

Degree: Master of Business Administration, Masters School / High School: Boston University 2004 to 2008

Skills

Drug Discovery • Chromatography • Hplc • Analytical Chemistry

Industries

Biotechnology

Resumes

Resumes

Wolfgang Goetzinger Photo 1

Director, Research

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Location:
Boston, MA
Industry:
Biotechnology
Work:
Amgen
Director, Research
Arqule Jan 1, 1997 - Dec 31, 2006
Director Analytical Chemistry
Education:
Boston University 2004 - 2008
Master of Business Administration, Masters Universität Des Saarlandes 1983 - 1993
Skills:
Drug Discovery
Chromatography
Hplc
Analytical Chemistry

Business Records

Name / Title
Company / Classification
Phones & Addresses
Wolfgang Goetzinger
Clerk
MASSEP.ORG, CORP
45 Vly Rd, Southborough, MA 01772
350 W 2 St #7, Boston, MA 02127

Publications

Us Patents

Coated Surface Comprising A Polyvinyl Alcohol (Pva) Based Covalently Bonded Stable Hydrophilic Coating

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US Patent:
6372353, Apr 16, 2002
Filed:
Nov 23, 1998
Appl. No.:
09/197896
Inventors:
Barry L. Karger - Newton MA
Wolfgang Goetzinger - Boston MA
Assignee:
Northeastern University - Boston MA
International Classification:
B32B 904
US Classification:
428447, 428521, 428 357, 428 3691, 4273722, 427387
Abstract:
Coatings suitable for surfaces such as are found in capillary electrophoresis columns and methods for their preparation are disclosed. A coated surface of the invention, preferably an interior surface of a microcapillary, generally includes a surface having an interconnected polymeric coating that includes a functional group attached to the surface and capable of copolymerizing with an organic compound in an organic solvent, and a polymer of the organic compound copolymerized with the functional group. The coating can be covalently or non-covalently attached to the surface and can further include an additional layer of coating material. Preferably, the organic compound is a vinyl ester, and most preferably, vinyl acetate, and the attached polymer forming the exposed surface of the coating is a polyvinyl alcohol, the hydroxyl groups of which can be further derivatized in any desired manner. The coating of the invention creates a new, stable surface, appropriate for CE columns or general surface modification. The coating is stable over a wide pH range and allows highly efficient grafting and/or adsorption of a variety of additional layers, if desired.

Polymer Mixtures For High Performance/High Temperature Separation In Capillary Electrophoresis, Especially For Long Read Dna Sequencing

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US Patent:
6476118, Nov 5, 2002
Filed:
Feb 18, 2000
Appl. No.:
09/507496
Inventors:
Barry L. Karger - Newton MA
Lev Kotler - Brighton MA
Wolfgang Goetzinger - Boston MA
Haihong Zhou - Boston MA
Zoran Sosic - Cambridge MA
Assignee:
Northeastern University - Boston MA
International Classification:
C08L 3104
US Classification:
524521, 204451, 204601, 525218
Abstract:
A method of separating a mixture of biopolymers of various lengths using a blend of two linear hydrophilic polymers, particularly polyacrylamides (LPA) or substituted polyacrylamides, one with high weight-average molecular mass and another with low weight-average molecular mass, each present at a low concentration but wherein the concentration of the high weight-average molecular mass LPA is above its entanglement threshold, is disclosed. The matrix is excellent for use in methods of nucleic acid analysis, particularly long read length DNA sequencing.

Rapid Method For Separation Of Small Molecules Using Reverse Phase High Performance Liquid Chromatography

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US Patent:
6497820, Dec 24, 2002
Filed:
Sep 12, 2000
Appl. No.:
09/600686
Inventors:
Wolfgang K. Goetzinger - Boston MA
James N. Kyranos - Wollaston MA
Assignee:
ArQule, Inc. - Woburn MA
International Classification:
B01D 1508
US Classification:
210635, 210656, 2101982
Abstract:
Disclosed is a rapid method for the separation of small organic compounds using gradient reverse phase HPLC. The method achieves a run time of one minute or less and a resolution with a peak production of at least 1 peak/2 seconds. The method is also able to achieve the separation of a compound from a mixture of compounds in an elution sample having a volume of 2 milliliters of less.

Polyvinyl Alcohol (Pva) Based Covalently Bonded Stable Hydrophilic Coating For Capillary Electrophoresis

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US Patent:
58403884, Nov 24, 1998
Filed:
May 22, 1997
Appl. No.:
8/861906
Inventors:
Barry L. Karger - Newton MA
Wolfgang Goetzinger - Boston MA
Assignee:
Northeastern University - Boston MA
International Classification:
C25B 900
US Classification:
428 3691
Abstract:
A coated microcapillary column for high performance electrophoresis is disclosed. A preferred microcapillary includes a fused silica capillary column, the inner surface of the column having an interconnected polymeric coating of a polyvinyl alcohol (PVA) based polymer covalently attached to the column wall by Si--O--Si bonds. The resulting coated microcapillary column has good hydrolytic and pH stability and minimizes electroosmotic flow and interactions between sample components and the capillary wall. Also disclosed are a method of forming a polymeric coating layer for any surface by polymerizing the appropriate organic compounds in an organic solvent and a method of forming a column with a hydrophilic polymeric coating by directly converting an attached hydrophobic polymeric coating material to a hydrophilic polymeric coating material.

Rapid Method For Separation Of Small Molecules Using Reverse Phase High Performance Liquid Chromatography

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US Patent:
59683619, Oct 19, 1999
Filed:
Feb 24, 1998
Appl. No.:
9/028401
Inventors:
Wolfgang K. Goetzinger - Boston MA
James N. Kyranos - Wollaston MA
Assignee:
ArQule, Inc. - Medford MA
International Classification:
B01D 1508
US Classification:
210635
Abstract:
The invention is a rapid method for the separation of small organic compounds using gradient reverse phase HPLC. The method of the invention achieves a run time of one minute or less and a resolution with a peak production of at least 1 peak/2 seconds. The method is also able to achieve the separation of a compound from a mixture of compounds in an elution sample having a volume of 2 milliliters or less.
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Wolfgang K Goetzinger from Boston, MADeceased Get Report