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Zhuoliang Liang Chen

from Belmont, MA
Age ~60
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Also known as:
Zhuoliang Liang Chenzhuo, Zhouliang Chen, Liang Chen Zhuoliang, Liang Chen Zhuo, Chen Zhuoliang
Phone and address:
20 Sargent Rd, Belmont, MA 02478
(617) 489-0826
Related to:
Wei Chen
Connected to:
Adalon Chen, 38Alicia A Chen, 38Alissa ChenAngi Chen, 33April F Chen, 42Arad Chen, 64Beidi Chen, 30Betty Y Chen, 80Bimei Chen, 48Bingyang Chen

Zhuoliang Chen Phones & Addresses

  • 20 Sargent Rd, Belmont, MA 02478 (617) 489-0826
  • Newtonville, MA
  • Watertown, MA
  • Mason, OH
  • Glen Ellyn, IL
  • Loveland, OH
  • Fairfield, OH
  • Cambridge, MA
  • Cincinnati, OH
  • Jamaica Plain, MA

Publications

Us Patents

Organic Compounds

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US Patent:
7419975, Sep 2, 2008
Filed:
Apr 6, 2005
Appl. No.:
11/099941
Inventors:
Mark Gabriel Palermo - Rindge NH, US
Sushil Kumar Sharma - West Orange NJ, US
Christopher Straub - Stow MA, US
Run-Ming Wang - Somerville MA, US
Leigh Scott Zawel - Hingham MA, US
Yanlin Zhang - Somerville MA, US
Zhuoliang Chen - Belmont MA, US
Yaping Wang - Boxborough MA, US
Fan Yang - Burlington MA, US
Wojciech Wrona - Waltham MA, US
Gang Liu - Waltham MA, US
Mark G. Charest - Cambridge MA, US
Feng He - Arlington MA, US
Assignee:
Novartis AG - Basel
International Classification:
A61K 31/407
A61K 31/437
A61K 31/55
C07D 487/04
C07D 471/04
US Classification:
514215, 514300, 514412, 514421, 540521, 540523, 540593, 546113, 548453
Abstract:
Novel compounds that inhibit the binding of the Smac protein to Inhibitor of Apoptosis Proteins (IAPs) of the formula I.

Organic Compounds

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US Patent:
7989441, Aug 2, 2011
Filed:
Jun 6, 2006
Appl. No.:
11/916887
Inventors:
Zhuoliang Chen - Belmont MA, US
Mark G. Palermo - Rindge NH, US
Sushil K. Sharma - West Orange NJ, US
Troy Smith - Nashua NH, US
Christopher S. Straub - Stow MA, US
Run-Ming D. Wang - Somerville MA, US
Yaping Wang - Boxborough MA, US
Leigh Zawel - Hingham MA, US
Assignee:
Novartis AG - Basel
International Classification:
A61K 31/44
C07D 223/12
C07D 211/76
US Classification:
51421103, 514349, 540527, 546297
Abstract:
The present disclosure relates to XIAP inhibitor compounds of the formula I.

Substituted Pyrazine-3-One-Derivatives As Iap Inhibitors

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US Patent:
8048886, Nov 1, 2011
Filed:
Dec 7, 2007
Appl. No.:
12/518184
Inventors:
Zhuoliang Chen - Cambridge MA, US
Run-Ming David Wang - Cambridge MA, US
Ming Chen - Cambridge MA, US
Christopher Sean Straub - Cambridge MA, US
Leigh Zawel - Cambridge MA, US
Assignee:
Novartis AG - Basel
International Classification:
A61K 31/4965
US Classification:
51425506, 544120, 544333, 544407, 548125, 548202, 548254, 548255, 548444, 548503, 548518, 549398, 585 26
Abstract:
The present invention relates to novel IAP inhibitor compounds of formula I:.

Organic Compounds

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US Patent:
8058272, Nov 15, 2011
Filed:
Dec 7, 2007
Appl. No.:
12/518195
Inventors:
Zhuoliang Chen - Cambridge MA, US
Run-Ming David Wang - Cambridge MA, US
Ming Chen - Cambridge MA, US
Christopher Sean Straub - Cambridge MA, US
Leigh Zawel - Cambridge MA, US
Assignee:
Novartis AG - Basel
International Classification:
C07D 401/02
A61K 31/44
US Classification:
5142372, 514312, 514333, 514334, 514349, 544131, 544333, 546152, 546256, 546261, 5462681, 546297
Abstract:
The present disclosure relates to XIAP inhibitor compound of the formula I:.

Inhibitors Of Iap

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US Patent:
8338440, Dec 25, 2012
Filed:
Apr 26, 2012
Appl. No.:
13/456274
Inventors:
Mark G. Palermo - Rindge NH, US
Sushil Kumar Sharma - West Orange NJ, US
Christopher Sean Straub - Stow MA, US
Run-Ming Wang - Cambridge MA, US
Leigh Zawel - Hingham MA, US
Yanlin Zhang - Somerville MA, US
Zhuoliang Chen - Belmont MA, US
Yaping Wang - Boxborough MA, US
Fan Yang - Burlington MA, US
Wojciech Wrona - Waltham MA, US
Gang Liu - Waltham MA, US
Mark G. Charest - Cambridge MA, US
Feng He - Shanghai, CN
International Classification:
A61K 31/427
A61K 31/4245
A61K 31/422
A61K 31/435
A61K 31/40
A61K 31/506
A61K 31/41
US Classification:
514275, 514277, 514364, 514365, 514374, 514381
Abstract:
Novel compounds that inhibit the binding of the Smac protein to Inhibitor of Apoptosis Proteins (IAPs) of the formula (I).

Dimeric Iap Inhibitors

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US Patent:
8445440, May 21, 2013
Filed:
Feb 23, 2011
Appl. No.:
13/033463
Inventors:
Christopher Straub - Cambridge MA, US
Zhuoliang Chen - Cambridge MA, US
Mark Palermo - Cambridge MA, US
Assignee:
Novartis AG - Basel
International Classification:
A61K 38/05
A61K 38/06
C07K 5/037
US Classification:
514 189, 514 219, 514 2191, 530323, 5462791
Abstract:
The present invention provides compounds of formula M-L-M′ (where M and M′ are each independently a monomeric moiety of Formula (I) and L is a linker). The dimeric compounds have been found to be effective in promoting apoptosis in rapidly dividing cells.

Pyridazinyl Derivatives As Smo Inhibitors

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US Patent:
8481542, Jul 9, 2013
Filed:
Jul 20, 2012
Appl. No.:
13/553870
Inventors:
Feng He - Shanghai, CN
Stefan Peukert - Arlington MA, US
Naeem Yusuff - Cambridge MA, US
Zhuoliang Chen - Belmont MA, US
Bharat Lagu - Acton MA, US
Assignee:
Novartis AG - Basel
International Classification:
C07D 403/14
C07D 401/14
A61K 31/501
A61P 35/00
US Classification:
51425202, 544238
Abstract:
The present invention relates to compounds of formula I:.

Smac Peptidometics Useful As Iap Inhibitors

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US Patent:
8546336, Oct 1, 2013
Filed:
Sep 7, 2012
Appl. No.:
13/606676
Inventors:
Zhuoliang Chen - Belmont MA, US
Mark G. Charest - Cambridge MA, US
Christine Hiu-Tung Chen - Waltham MA, US
Miao Dai - Shanghai, CN
Feng He - Shanghai, CN
Huangshu Lei - Durham NC, US
Ly Luu Pham - Arlington MA, US
Sushil Kumar Sharma - West Orange NJ, US
Christopher Sean Straub - Stow MA, US
Run-Ming David Wang - Cambridge MA, US
Fan Yang - West Roxbury MA, US
Leigh Zawel - Cambridge MA, US
Assignee:
Novartis AG - Basel
International Classification:
A61K 38/00
US Classification:
514 193, 514 2191, 5462791, 546256, 548236, 548200, 548181, 544335, 544329
Abstract:
The present invention is directed to a compound of the formula:.
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Zhuoliang Liang Chen from Belmont, MA, age ~60 Get Report