Inventors:
Gerald John Spangrude - Salt Lake City UT, US
Birgitta H. Mitchell - Salt Lake City UT, US
Jared Manning - Twin Falls ID, US
International Classification:
C12N 5/0783
C12N 5/0789
C12N 5/0775
Abstract:
This disclosure describes methods for differentiating T cells and NK cells in vitro from hematopoietic stem cells or precursor cells. The technology is directed to methods for the production of selected populations of lymphocytes, such as T cells and NK cells. The availability of such cell populations allows for the complete reconstitution of a depleted, defective or missing lymphocyte population in a patient.