Qinggang Zeng

8308798, Nov 13, 2012

Dec 10, 2009

12/635471

Rafael Pintor - Mission Viejo CA, US
Mark Chau - Aliso Viejo CA, US
Travis Oba - Corona CA, US
August Yambao - Temecula CA, US
Louis Campbell - Santa Ana CA, US
Tammy Huntley - Foothill Ranch CA, US
Qinggang Zeng - Irvine CA, US
Carey Cristea - Irvine CA, US
Faisal Kalam - Corona CA, US

Edwards Lifesciences Corporation - Irvine CA

A61F 2/24

623 218, 623 217

A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available to valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment. A catheter-based system and method for deployment is provided.

8348998, Jan 8, 2013

Jun 23, 2010

12/821628

Rafael Pintor - Mission Viejo CA, US
Mark Chau - Aliso Viejo CA, US
Travis Oba - Corona CA, US
August Yambao - Temecula CA, US
Louis A. Campbell - Santa Ana CA, US
Tammy Huntley - Foothill Ranch CA, US
Qinggang Zeng - Irvine CA, US
Carey Cristea - Irvine CA, US
Faisal Kalam - Corona CA, US

Edwards Lifesciences Corporation - Irvine CA

A61F 2/24

623 211, 623 111, 623 124, 623 126

A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable coupling stent, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the coupling stent attached thereto. The coupling stent may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes a hollow two-piece handle through which a balloon catheter passes. A valve holder is stored with the heart valve and the handle easily attaches thereto to improve valve preparation steps.

8591567, Nov 26, 2013

Nov 13, 2009

12/618023

Mark Chau - Aliso Viejo CA, US
Travis Oba - Corona CA, US
Tammy Huntley - Foothill Ranch CA, US
Qinggang Zeng - Irvine CA, US
August Yambao - Temecula CA, US
Rafael Pintor - Mission Viejo CA, US

Edwards Lifesciences Corporation - Irvine CA

A61F 2/06
A61F 2/24
A61M 31/00

623 112, 6041038, 623 211

A system for expanding a device in a conduit or orifice of a human body includes an expansion device that is movable from a first configuration to a second configuration. External surfaces of the expansion device can collectively have a non-cylindrical cross-section relative to a main axis of the expansion device, such that the external surfaces of the expansion device generally conform to the anatomical shape of the conduit or orifice when the expansion device is in the second configuration.

8641757, Feb 4, 2014

Jun 23, 2011

13/167639

Rafael Pintor - Mission Viejo CA, US
Michael J. Scott - San Diego CA, US
Thomas Chien - San Jose CA, US
Harvey H. Chen - Irvine CA, US
August R. Yambao - Temecula CA, US
Lawrence J. Farhat - Carlsbad CA, US
Andrew Phung - Brea CA, US
William C. Brunnett - Mission Viejo CA, US
Carey L. Cristea - Lake Forest CA, US
Sara M. Walls - Draper UT, US
Kevin W. Zheng - Torrance CA, US
Faisal Kalam - Corona CA, US
Qinggang Zeng - Irvine CA, US

Edwards Lifesciences Corporation - Irvine CA

A61F 2/24

623 211, 623 217, 623 218

A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the frame attached thereto. The frame may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes an integrated handle shaft and balloon catheter. A valve holder is stored with the heart valve and the handle shaft easily attaches thereto to improve valve preparation steps.

20100249908, Sep 30, 2010

Mar 2, 2010

12/716062

Mark Chau - Aliso Viejo CA, US
Qinggang Zeng - Irvine CA, US

Edwards Lifesciences Corporation - Irvine CA

A61F 2/82

623 126

An exemplary two-stage prosthetic heart valve system has a radially expandable base stent implanted within a native valve annulus. The base stent desirably has three position markers projecting in the axial direction from the outflow end of the base stent to assist in aligning the stent with respect to the commissures of the native valve. The two-stage heart valve system also has a valve component that is delivered to and mounted within the base stent in a separate or sequential operation after the base stent has been anchored within the annulus. The valve component in certain embodiments comprises a hybrid valve component that includes a conventional, non-expandable surgical valve that is modified to include an expandable coupling stent that can be expanded to engage the inner surface of the base stent, thereby anchoring the valve component to the base stent.

20110147251, Jun 23, 2011

Dec 15, 2010

12/969238

Fred Hodshon - Orange CA, US
Rafael Pintor - Mission Viejo CA, US
August Yambao - Temecula CA, US
Abhishek Gautam - Irvine CA, US
Louis A. Campbell - Santa Ana CA, US
Lawrence Farhat - Carlsbad CA, US
Tammy Huntley - Foothill Ranch CA, US
Faisal Kalam - Corona CA, US
Travis Oba - Corona CA, US
Qinggang Zeng - Irvine CA, US

EDWARDS LIFESCIENCES CORPORATION - Irvine CA

B65D 85/00

206438

Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within a jar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. Contrary to previous designs, in one embodiment the valve holder is directed downward into the jar, and the valve is retained with an inflow end upward. The valve may have flexible leaflets, and a leaflet parting member on the end of the shaft extends through the leaflets and couples with the valve holder. The assembly of the packaging sleeve, valve, and holder can then be removed from the jar and a valve delivery tube connected with the holder, or to the leaflet parting member. The packaging sleeve may be bifurcated into two halves connected at a living hinge to facilitate removal from around the valve/holder subassembly. The packaging system facilitates attachment of the valve delivery tube for use in a quick-connect valve implant procedure.

20120150288, Jun 14, 2012

Feb 23, 2012

13/403537

Fred Hodshon - Orange CA, US
Rafael Pintor - Mission Viejo CA, US
August Yambao - Temecula CA, US
Abhishek Gautam - Irvine CA, US
Louis A. Campbell - Santa Ana CA, US
Lawrence Farhat - Carlsbad CA, US
Tammy Huntley - Foothill Ranch CA, US
Faisal Kalam - Corona CA, US
Travis Oba - Corona CA, US
Qinggang Zeng - Irvine CA, US

EDWARDS LIFESCIENCES CORPORATION - Irvine CA

A61F 2/24

623 211

Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within a jar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. Contrary to previous designs, in one embodiment the valve holder is directed downward into the jar, and the valve is retained with an inflow end upward. The valve may have flexible leaflets, and a leaflet parting member on the end of the shaft extends through the leaflets and couples with the valve holder. The assembly of the packaging sleeve, valve, and holder can then be removed from the jar and a valve delivery tube connected with the holder, or to the leaflet parting member. The packaging sleeve may be bifurcated into two halves connected at a living hinge to facilitate removal from around the valve/holder subassembly.

20130190862, Jul 25, 2013

Mar 12, 2013

13/797591

Rafael Pintor - Mission Viejo CA, US
Michael J. Scott - San Diego CA, US
Qinggang Zeng - Irvine CA, US
Grace Myong Kim - Garden Grove CA, US
Visith Chung - Chino Hills CA, US
Louis A. Campbell - Santa Ana CA, US
David S. Lin - Irvine CA, US
Peng Norasing - Corona CA, US
Edwin T. Ta - St. Louis Park MN, US

A61F 2/24

623 218

A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable stent frame, thereby enabling attachment to the annulus without sutures. The prosthetic valve may be a commercially available valve with a sewing ring and the stent frame attached thereto. The stent frame may expand from a conical deployment shape to a conical expanded shape, and may have a cloth covering its entirety as well as a plush sealing flange around its periphery to prevent paravalvular leaking.