Resumes
Resumes
Shiteng Duan Phones & Addresses
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South San Francisco, CA
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San Mateo, CA
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San Diego, CA
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La Jolla, CA
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Fremont, CA
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Santa Cruz, CA
Publications
Us Patents
Immune Cell Receptor Antibodies Conjugated To High Affinity Siglec-Ligands
View pageUS Patent:
20230037822, Feb 9, 2023
Filed:
Oct 28, 2020
Appl. No.:
17/755382
Inventors:
- La Jolla CA, US
Maidul Islam - San Diego CA, US
Fabian Pfrengle - Klosterneuburg, AT
Matthew Macauley - Edmonton, CA
Shiteng Duan - San Diego CA, US
Britni Arlian - Spring Valley CA, US
Maidul Islam - San Diego CA, US
Fabian Pfrengle - Klosterneuburg, AT
Matthew Macauley - Edmonton, CA
Shiteng Duan - San Diego CA, US
Britni Arlian - Spring Valley CA, US
Assignee:
The Scripps Research Institute - La Jolla CA
International Classification:
A61K 47/68
A61P 37/08
A61P 37/08
Abstract:
Described herein are Siglec ligand-antibody conjugates and compositions thereof that are useful for suppressing unwanted immune responses such as allergies and anaphylaxis.
Desensitizing Mast Cells By Co-Presentation Of Antigens With High Affinity Mast Cell Siglec Ligands
View pageUS Patent:
20190151444, May 23, 2019
Filed:
Jul 7, 2017
Appl. No.:
16/315796
Inventors:
- La Jolla CA, US
Shiteng Duan - San Diego CA, US
Matthew MacAuley - San Diego CA, US
Corwin Nycholat - San Diego CA, US
Shiteng Duan - San Diego CA, US
Matthew MacAuley - San Diego CA, US
Corwin Nycholat - San Diego CA, US
International Classification:
A61K 39/385
A61K 39/395
A61K 47/69
A61K 31/702
A61K 39/395
A61K 47/69
A61K 31/702
Abstract:
Compositions and methods are described herein that are useful for treating and inhibiting allergic conditions, including reducing the incidence of mast cell mediated anaphylaxis in subjects. The compositions include a carrier that displays an antigen and a Siglec ligand that binds to a Siglec on a mast cell.